DNA packaging Flashcards

1
Q

How do prokaryotic cells divide

A

fission

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2
Q

fission

A
  1. they have one circular chromosome
  2. as DNA replicates it attaches to membrane
  3. new plasma membrane between attached points
  4. Cytokinesis separates the one cell into two
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3
Q

How do eukaryotes divide

A

mitosis , meiosis

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4
Q

constriction point of a chromosome

A

centromere

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5
Q

arms of chromosome

A

short - p arm
long - q arm

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6
Q

Chromatin

A

DNA + Histone + other proteins making up chromosomes

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7
Q

What energy is needed for coiling

A

Histones provide energy

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8
Q

What is a histone

A

positively charged protein, that DNA is compact chromosomal DNA

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9
Q

charge of DNA

A

negative due to phosphate groups in its phosphate sugar backbone

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10
Q

Nucleosome

A

repeating structural and functional unit of chromatin
- 9 histones, 166 base pairs

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11
Q

functions of chromatin

A
  • package DNA
  • strengthen DNA for division
  • control gene expression and replication
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12
Q

Two forms chromatin is divided between

A

Heterochromatin (condensed)
Euchromatin (Extended)

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13
Q

Two mechanisms by which chromatin is made more accessible

A
  • histones enzymatically modified
  • histones displaced by chromatin remodelling complexes
    = reversible
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14
Q

Prometaphase

A

Nuclear envelop breaks down
microtubules attach to chromosome

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15
Q

Metaphase

A

chromosomes line up in the centre on the metaphase plate
spindle fibres are attached

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