DNA & Cell Cycle Flashcards

1
Q

interphase

A

the longest part of a cell’s life - the cell grows and makes a copy of its DNA (G1+S+G2)

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2
Q

G1 & G2

A

cell growth & copies organelles

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3
Q

S1

A

synthesis of DNA

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4
Q

mitosis

A

the nucleus divides

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5
Q

prophase

A

DNA condenses into chromosomes, nuclear membrane disappears

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6
Q

metaphase

A

chromosomes line up in the center

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7
Q

anaphase

A

chromosomes are separated to opposite poles of the cell

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8
Q

telophase

A

two new nuclei are created

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9
Q

cytokinesis

A

the cell completely divides into two daughter cells, the cytoplasm divides

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10
Q

cancer

A

disruptions in the cell cycle are when the cell loses control of cell division & cannot stop dividing – results in abnormal cell growth called tumors = cancer

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11
Q

mitosis

A

creates body cells (2 daughter cells)

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12
Q

meiosis

A

creates sex gametes (sperm & egg) [single cell divides twice, produces 4 cells with half of the genetic info]

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13
Q

how many divisions does mitosis have?

A

1

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14
Q

how many divisions does meiosis have?

A

2

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15
Q

how many daughter cells does mitosis result in & are they identical or unique?

A

2 identical daughter cells

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16
Q

how many daughter cells does meiosis result in & are they identical or unique?

A

4 unique daughter cells

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17
Q

what type of reproduction does mitosis go thru?

18
Q

what type of reproduction does meiosis go thru?

19
Q

things that occur that cause genetic variation

A

crossing over, segregation of alleles, independent assortment

20
Q

segregation of alleles

A

alleles separate & move into a different haploid gamete sex cell

21
Q

independent assortment

A

traits don’t follow each other, they move independently

22
Q

DNA structure

A

double helix, anti-parallel strands, backbone = sugar & phosphate, steps = paired bases

23
Q

cell cycle has

A

regulated cell growth, replication & division

24
Q

G0

A

the resting phase where cells convert glucose to ATP, make proteins & other general processes

25
mutations
mistakes in chromosomes & changes in DNA cause mutations
26
checkpoint
where the DNA is checked & the cell cycle can be stopped
27
how many chromosomes do body cells have
46
28
how many chromosomes do sex cells have
23
29
does mitosis or meiosis cause genetic variation
meiosis
30
purpose of mitosis
growth & repair
31
purpose of meiosis
sexual reproduction
32
point mutation
where one nucleotide is changed so only one amino acid may be affected
33
substitution
one nucleotide takes the place of another in the sequence & can either result in a change or no change
34
frameshift mutation
Where a nucleotide is deleted or inserted into the DNA, shifting everything up or down. Shifts or changes the way a DNA sequence is read and transcribed. Changes the amino acid sequence starting from the mutation point. Protein is usually non-functional (doesn’t work)
35
insertion
when a base is added
36
deletion
when a base is removed
37
what causes chromosomal mutations
problems that occur during meiosis, mutagens (chemicals, radiation, UV, etc)
38
what are the results of chromosomal mutations
change in # of chromosomes in a cell, change in the structure of the chromosome, affects entire chromosome & protein production
39
translocation
when a portion of one chromosome is transported to another chromosome
40
nondisjunction
the failure of homologous chromosomes to separate properly during cell division. It produces individuals with either extra or missing chromosomes