DM T1&2 Flashcards
- polyuria
- polydipsia
- weight loss
- lowered plasma vol.
- hypotension
- loss of subcutaneous fat and muscle wasting
Diabetic Mellitus Type 1
dysfunction of peripheral sensory nerves/lower extremity
paresthesias
caused by dehydration and hyperosmolality
ketoacidosis
- polyruria
- polydypsia
- polyphagia
- obese diabetic
- mild hypertension
Diabetic Mellitus Type 2
promotes formation of ketone formation
carnitine palmitoyl transferase 1
gasping character breathing
kussmaul respiration
in the kidneys not filtering the blood from excess products
prerenal azotemia
needed to correct acidosis
sodium bicarbonate
leads activation of protein kinase c
diacylglycerol
presence of albumin in pee
macroalbuminuria
presence of protein in pee
proteinuria
a common associated finding
dyslipidemia
feet ulcers due to lack og protective mechanisms, caused by PAD
gangrene of the feet
Diabetic Ketoacidosis manifestations:
- ketotic odor / fruity breath
- tachycardia
- dry mouth / dehydration
- acute pancreatitis
- cerebral edema
Ocular Complications:
- glaucoma
- diabteic cataract
neovascularization of the iris
glaucoma
nonenzymatic glycosylation of lens protein
diabteic cataract
MICROVASCULAR COMPLICATIONS
retinopathy
neuropathy
nephropathy
MACROVASCULAR COMPLICATIONS
coronary artery disease (cad)
peripheral arterial disease (pad)
cerebrovascular disease
NONVASCULAR COMPLICATIONS
gastroparesis
infections
skin changes
