Disorders of the Respiratory System Flashcards

1
Q

hypoxia

A

a deficiency of oxygen in tissues, often a consequence of respiratory disorders

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2
Q

hypoxemic hypoxia

A

describes low pO2 in arterial blood due to high alitude, airway obstruction, fluid in lungs, carbon monoxide poisoning

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3
Q

ischemic hypoxia

A

due to decreased blood circulation

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4
Q

anemic hypoxia

A

occurs if blood cannot carry enough oxygen because of anemia, hemorrhage, insufficient hemoglobin

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5
Q

histotoxic hypoxia

A

occurs when tissues cant use oxygen because a toxin agent is present

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6
Q

principal symptom of hypoxia

A

cyanosis, which produces blue skin

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7
Q

breathing pure oxygen for an extended period of time leads to

A

oxygen toxicity

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8
Q

oxygen toxicity generates

A

free radicals that can cause problems with central nervous system which could produce coma or even death

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9
Q

scuba divers

A

must balance a mixutre of oxygen and nitrogen to avoid this problem

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10
Q

Chronic Obsructive Pulmonary Disease

A

any disorder that is characterized by chronic and recurrent obstruction of air flow that causes a significant reduction in ventiliation

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11
Q

COPD causes

A

smoking, exposure to second had smoke, air pollution, occupational exposure to airborn irratants, or allergens

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12
Q

COPD symptoms

A

include coughing, frequent respiratory infections, and hypoventilation

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13
Q

“pink puffers”

A

tend to be very thin and exhibit normal blood gases

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14
Q

“blue bloaters”

A

tend to be stocky and exhibit cyanosis because of hypoxia

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15
Q

routin treatment for COPD

A

with bronchodilators and aerosol corticosteroids that are inhaled

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16
Q

chronic bronchitis

A

inflammation of the bronchi which is usually caused by smoking

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17
Q

effects of chronic bronchitis

A
  • goblet cells become enlarged and produce excess mucus
  • cilia are immoblized and reduce in number
  • alveolar macrophages incapacitated by cigarette smoke
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18
Q

in chronic bronchitis the sputum

A

provides a growht medium for bacteria which leads to chronic infection

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19
Q

emphysema

A

involves the permanent enlargement of alveoli due to long term exposure to airborne irritants, especially tabacco smoke

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20
Q

in emphysema the alveolar walls

A

break down and lose elasticity

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21
Q

in emphysema the alveoli

A

remain inflated during expiration and obstruct out-flowof air

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22
Q

in emphysema the damage to pulmonary capillaries

A

causes enlargement of the right ventricle

23
Q

in emphysema ventilation

A

becomes inceasingly difficult and a “barrel-chest” develops

24
Q

asthma

A

an immune response triggered by allergens (allergic asthma) or by infection, drugs, exercise, or cold, dry air (non-allergic asthma)

25
Q

astma demographics

A

most common chronic illnes of children, especiallly by young boys with 50% of cases developing before age 10

26
Q

asthma is characterized by

A

chronic airway inflammation and airway obstruction

27
Q

in asthma muscle spasms

A

trigger bronchoconstriction (in tertiary bronchi and bronchioles)

28
Q

in asthma excess mucus secretion

A

clogs bronchioles and can lead to suffocation

29
Q

asthma treatment

A

involves inhaling epinephrine to relax bronchioles and open airway and cotcosteroids to reduce inflammation

30
Q

pneumonia

A

an acute infection of alveoli caused by viruses, bacteria, or fungi

31
Q

in pneumonia alveoli

A

fill with fluid and dead leukocytes, reduces ventilation and gas exchange

32
Q

pneumonia demographics

A

especially dangerous to infants, the elderly, and people with compromised immune systems

33
Q

tuberculosis

A

an infection transmitted by inhalation

34
Q

in tuberculosis lung tissue

A

is destroyed and replaced with fibrous connective tissue; reduces elastic recoil and ventilation

35
Q

recent resurgence of TB

A

correlates with a risk in HIV infection and the development of antibiotic resistant strains of the bacteria

36
Q

lung cancer develops

A

primarily from cigarette smoke, although long-term exposure to airborne irritants, including secondhand smoke, is responsible for about 15% of all cases

37
Q

squamous cell carcinoma

A

develops in bronchial epithelium and spreads to the bronchial walls where bleeding lesions occur

38
Q

adenocarcinoma

A

develops in bronchial glands and alveolar cells

39
Q

smal cell carcinoma

A

originates in the the primary bronchi, but invades the mediastinum and quickly mestasisizes to other organs

40
Q

cystic fibrosis

A

a genetic disease that reduces the body’s ability to transport chloride ions across the plasma membrane of epithelial cells

41
Q

5% of the population carries

A

a detective gene that still allows these cells to make chloride pumps, but the pumps dont get installed correctly in the plasma membrane
-cystic fibrosis

42
Q

cystic fibrosis is characterized by

A

salty sweat

43
Q

in cystic fibrosis cells in the respiratory passageways produce

A

heavy mucus secretions that clog cilia in the airways and make breathing difficult

44
Q

in cystic fibrosis the leading cause of death is

A

lung disease that develops by age 30

45
Q

high altitude sickness

A

occurs when the altitude increases, because air pressure and pO2 decreases

46
Q

in high altitude sickness less oxygen reaches blood and causes

A

shortness of breath, severe headache, fatigue, nausea, dizziness

47
Q

nitrogen narcosis

A

affects underwater workers who breathe air under high pressure

48
Q

pressurized air tanks create

A

positive intrapulmonary pressure that allows a person to inspire with minimal thoracic activity

49
Q

pressurized air allows nitrogen gas to

A

dissolve easily in blood, in adipose tissue, in myelin of brain

50
Q

pressurized air causes

A

giddiness and disorientation

51
Q

decompression sickness

A

deep water divers who surface too quickly can suffer from this

52
Q

in decompression sickness nitrogen

A

rapidly leaves body fluids and produces dangerous gas bubbles in joints, bones, muscles, and pulmonary capillaries

53
Q

decompression sickness can cause

A

pain, dyspnea or loss of conciousness