Disorders of the Respiratory System Flashcards
hypoxia
a deficiency of oxygen in tissues, often a consequence of respiratory disorders
hypoxemic hypoxia
describes low pO2 in arterial blood due to high alitude, airway obstruction, fluid in lungs, carbon monoxide poisoning
ischemic hypoxia
due to decreased blood circulation
anemic hypoxia
occurs if blood cannot carry enough oxygen because of anemia, hemorrhage, insufficient hemoglobin
histotoxic hypoxia
occurs when tissues cant use oxygen because a toxin agent is present
principal symptom of hypoxia
cyanosis, which produces blue skin
breathing pure oxygen for an extended period of time leads to
oxygen toxicity
oxygen toxicity generates
free radicals that can cause problems with central nervous system which could produce coma or even death
scuba divers
must balance a mixutre of oxygen and nitrogen to avoid this problem
Chronic Obsructive Pulmonary Disease
any disorder that is characterized by chronic and recurrent obstruction of air flow that causes a significant reduction in ventiliation
COPD causes
smoking, exposure to second had smoke, air pollution, occupational exposure to airborn irratants, or allergens
COPD symptoms
include coughing, frequent respiratory infections, and hypoventilation
“pink puffers”
tend to be very thin and exhibit normal blood gases
“blue bloaters”
tend to be stocky and exhibit cyanosis because of hypoxia
routin treatment for COPD
with bronchodilators and aerosol corticosteroids that are inhaled
chronic bronchitis
inflammation of the bronchi which is usually caused by smoking
effects of chronic bronchitis
- goblet cells become enlarged and produce excess mucus
- cilia are immoblized and reduce in number
- alveolar macrophages incapacitated by cigarette smoke
in chronic bronchitis the sputum
provides a growht medium for bacteria which leads to chronic infection
emphysema
involves the permanent enlargement of alveoli due to long term exposure to airborne irritants, especially tabacco smoke
in emphysema the alveolar walls
break down and lose elasticity
in emphysema the alveoli
remain inflated during expiration and obstruct out-flowof air