Accessory Structures of the Digestive System Flashcards
the liver is
the heaviest gland in the body with a mass of about 1.4 kilograms
the liver is located
in upper right quadrant of abdominal cavity beneath diaphragm
the liver is covered by
peritoneum and dense irregular connective tissue
the liver is divided into
large right lobe and smaller left lobe by falciform ligament
______ lobe is subdivided into 2 smaller lobes
right lobe
liber lobes are composed of
hexagonal functional units called lobules
hepatocytes are arranged
radially around a central vein and they produce bile
__________ surround hepatocytes
wide, thin-walled blood sinusoids
sinusoids contain
hepatic macrophages (kupffer’s cells) that remove worn-out blood cells, bacteria, toxic substances from blood
sinusoids receive blood from
hepatic (portal) triad
branch of hepatic artery supplies
Oxygen rich blood
branch of hepatic portal vein supplies
nutrient rich blood from GI tract
bile ductule collects
bile
blood from stomach and small intestine can be
filtered by the sinusoids
bile (digestive substance) is secreted into
bile canaliculi
bile canaliculi empty into
bile ductules
bile ductules merge to form
right and left hepatic ducts
hepatic ducts unite and
exit the liver as the common hepatic duct
bile is
a mixure of water, bile acids, bile salts, cholesterol, lecithin, and bile pigments (yellow, brown, olive green)
bile salts play an important role in
the emulsification and absorption of fats
principal bile pigment is
bilirubin which is derived from breakdown of hemoglobin; gives fecal matter color
other components of bile become
wastes that get eliminated in feces
the liver carries out numeous
functions
the liver controls carb, lipid, and protein
metabolism
liver removes
drugs and hormones from blood
liver synthesizes
biles
liver excretes
bilirubin
liver stores
glycogen, vitamins, and minerals
liver phagocytosizes
worn out blood cells
the gallbladder is
a small, pear-shaped sac attached to the ventral surface of the liver
the cystic duct from the gallbladder joins
with the common hepatic duct from the liver to form the common bile duct
the gallbladder
STORES and concentrates biles
bile travels through hepatopancreatic ampulla into
small intestine
between meals, hepatopancreatic sphincter (of Oddi) remains
closed so bile accumulates in gallbladder
the pancreas is
an oblong, spongy gland located posterior and inferoir to the stomach
pancreatic secretions are collected by
small ducts that empty into the pancreatic duct which usually joins the common bils duct to form the hepatopancreatic ampulla
smaller accessory pancreatic ducts opens
independently into small intestine
the pancreas is made up of
clusters of cells
pancreatic islets (of Langerhans) form
endocrine portion of pancreas and they secrete the hormones glucagon and insulin
acini form the
exocrine portion of the pancreas and they secrete between 1200 and 1500 mL of pancreatic juice per day
pancreatic juice is a
alkaline mixutre of water, salts, sodium bicarbonate, and a variety of digestive enzymes, many of which are released in an inactive form
epithelial cells release
bicarbonate ions to neutralize hydrochloric acid produced by stomach
pancreatic amylase splits
starch molecules into moleculesof dissacharide maltose
pancreatic lipase splits
emulsified fats into fatty acids and monglycerides
nucleases convert
DNA and RNA molecules into nucleotide monomers
trypsinogen is converted
into trypsin to split proteins into smaller peptides
chrmotrypsingen is converted into
chymotrypsin to split proteins into smaller particles
procarboxypeptidase is converted into
carboxypeptidase to break peptides into individual amino acids
the secretion of pancreatic juice is regulated by
nervous and hormonal mechanisms
parasympathetic impulses stimulate the pancreas to
secrete pancreatic juice
acidic chyme in the duodenum stimulates the
intestinal mucosa to release secretin, which triggers the release of pancreatic juice that is rich in bicarbonate ions
secretin
neutralizes acidity of chyme
fatty chume in the duodenum stimulates the
intestinal mucosa to release cholecystokinin (CCK) which causes the galbladder to release bile, stimulates the secretion of pancreatic enzymes, and relaxes the hepatopancreatic sphincter