Disorders of the NS Caused By Alcohol, Drugs, etc

Question 1

True or false: Drinking is more often a consequence of depression.

Answer 1

False. Depression is more often a consequence of drinking

Adams

Question 2

Flushing reaction in asians secondary to alcohol intake is due to a deficiency of?

Answer 2

Aldehyde dehydrogenase activity

Question 3

State the expected symptom for the following alcohol blood level

30 mg/dL

Answer 3

Mild euphoria

Question 4

State the expected symptom for the following alcohol blood level

50 mg/dL

Answer 4

Mild incoordination

Question 5

State the expected symptom for the following alcohol blood level

100mg/dL

Answer 5

Ataxia

Question 6

State the expected symptom for the following alcohol blood level

200mg/dL

Answer 6

Confusion

Reduced levels of mental activity

Question 7

State the expected symptom for the following alcohol blood level

300mg/dL

Answer 7

Stupor

Question 8

State the expected symptom for the following alcohol blood level

400mg/dL

Answer 8

Deep anesthesia

Potentially fatal

Question 9

What are the receptors that are sensitive to alcohol?

Answer 9

GABA receptors
NMDA receptors
Serotonin receptors (possibly)

Question 10

The effect of chronic administration of alcohol is to increase the number of neuronal ______ channels in the cell membrane.

Answer 10

Calcium

Question 11

In alcoholic “blackouts”, what kind of memory is affected?

A) Short-term (retentive) memory
B) Immediate memory
C) Long-term memory

Answer 11

A) Short-term (retentive) memory

Question 12

The use of hemodialysis should be considered in what context of alcoholic intoxication?

Answer 12

Comatose patients w/ BAC >500mg/dL
*esp. if w/ acidosis

Or (+) ingestion of methanol, ethylene glycol, other dialyzable drug

Question 13

Which type of alcohol ingestion can result in

1. Characteristic damage to retinal ganglion cells
2. Putaminal necrosis, dystonia, parkinosnism in survivors

A) Amyl and isopropyl alcohol
B) Methyl alcohol (methanol, wood alcohol)
C) Ethylene glycol

Answer 13

B) Methyl alcohol (methanol, wood alcohol)

Question 14

More than 90% of alcohol withdrawal seizures occur during ____ post-cessation, with a peak incidence between ____

Answer 14

7-48 hours post cessation

Peak: 13-24 h

Question 15

Which of the following is TRUE regarding lab findings in alcohol withdrawal patients?

A) Low blood glucose is a common finding
B) Serum Na levels are frequently altered
C) Most patients show some degree of HYPOmagnesemia, LOW PCO2, HIGH arterial pH
D) No abnormalities on MRI are seen

Answer 15

True: C) Most patients show some degree of HYPOmagnesemia, LOW PCO2, HIGH arterial pH

A) Low blood glucose is AN INFREQUENT finding
B) Serum Na levels are INFREQUENTLY altered
D) No abnormalities on MRI are seen - Enlargement of the 3rd and lateral ventricles is a common finding

Question 16

On Leukoencephalopathy secondary to Heroin use:

Most instances of this leukoencephalopathy are the result of inhalation of heated heroin vapor in a practice known as ________.

Ropper, Allan H.; Samuels, Martin A.; Klein, Joshua. Adams and Victor’s Principles of Neurology 11th Edition (p. 1226). McGraw-Hill Education. Kindle Edition.

Answer 16

“Chasing the dragon”