Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

MD2S3: Physiology 203 > Disorders of Pancreatic Hormones > Flashcards

Disorders of Pancreatic Hormones Flashcards

1
Q

Cause of T1DM

A

Lack of Insulin Secretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

T1DM
What is Diabetic Ketoacidosis (DKA)?

A

Hyperglycemia and Metabolic Acidosis

Frequently occurs in T1DM patients

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

T1DM
Common presentations of DKA

A

Laboured Respiration
Abdominal Pain
Hypotension
Signs of Severe Dehydration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

T1DM
How is DKA treated?

A

Insulin
Fluids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

T1DM
T1DM can be attributed to ____ and ____ factors

A

__Genetic__
__Environment__

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

T1DM
Mechanism of occurence

A

T- and B-cell mediated immune destruction of Pancreatic β cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

T1DM
Why do autoimmune reactions occur?

A

Autoantigens from Pancreatic β cells are targeted by immune system due to molecular mimicry after a viral infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

T1DM
Why does dehydration occur in T1DM?

A

Osmotic Diuresis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

T1DM
Describe the process of Osmotic Diuresis

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

T1DM
Chronic Complications

A

Retinopathy
Diabetic Kidney Disease
Peripheral Neuropathy
Autonomic Neuropathy
Accelerated Atherosclerosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Fill Out

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Causes of T2DM

A

Initially: Peripheral Insulin Resistance
Later: High Glucagon and Deficient Insulin Secretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

T2DM
Other Pathophysiological Causes (Besides Insulin Resistance and ↑Glucagon Levels)

A

Excessive Hepatic Glucose Production
Abnormal Fat Metabolism
Systemic Low-Grade Inflammation
Genetics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

T2DM
Typical Characteristics of patients

A

Older than 40
Obese with Predominately Abdominal fat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

T2DM
How can it be diagnosed?

A

Laboratory Testing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

T2DM
Symptoms

A

Polyuria
Polydipsia (Increased Thirst)
Polyphagia (Increased Hunger)
Weight Gain

17
Q

T2DM
Risk factors

A

Obesity
Sedentary Lifestyle
Diet
Smoking
Alcohol Consumption
Sleep Deprivation
Genetic Factors

18
Q

T2DM
What causes Insulin Resistance?

A

Reduced Insulin Receptors
Cytokines secreted by Adipocytes
Leptin Deficiency
High Cortisol
Inadequate Pacreatic Secretion

19
Q

T2DM
Acute Complications

A

Osmotic Diuresis
Volume Depletion
Electrolyte Disorders
Hypotension
Increased Risk of Infection

20
Q

T2DM
Chronic Complications

A

Microangiopathy/Macroangiopathy/Ischemia
Retinopathy
Diabetic Kidney Disease
Autonomic Neuropathy
Accelerated Atherosclerosis
Peripheral Neuropathy

21
Q

How can C-Peptide be used to distinguish between T1DM and T2DM?

A

T1DM: Little to no C-Peptide
T2DM: C-Peptide present

22
Q

Characteristics of Prediabetes

A

HBA1C = 5.7-6.4%
Fasting Plasma Glucose = 100-125 mg/dL
Impaired Glucose Tolerance (140-199 mg/dL during 75g glucose tolerance test)

MD2S3: Physiology 203 (13 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions