dislipidemias Anticuerpos monoclonales anti PCSK9 Flashcards

1
Q

cuales son

A

Evolocumab. Alirocumab.

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2
Q

mecanismo de accion

A

recaptura de ldl plasmatico

La PCSK9 es una enzima proteasa que favorece la destrucción de receptores LDL.

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3
Q

indicaciones

A

Tx de hipercolesterolemias primarias.

  • Tx de pacientes con hipercolesterolemia primara que no responden de manera
    adecuada a las estatinas.
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4
Q

EA

A
  • Reacciones cutáneas locales.
  • ⬆ de enzimas hepáticas.
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5
Q

se administra cada

A

2 semanas

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