Antifimicos Flashcards

1
Q

isoniazida MoA

A

Inhibición de la síntesis de ácido micólico (pared celular)
Bactericida

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2
Q

isoniazida no requiere

A

ajuste en falla renal

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3
Q

isoniazida EA

A

hepatotoxico
def Vit b6: NEUROPATIA PERIFERICA
Sindrome de lupus like

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4
Q

rifampicina MoA

A

Inhibición de ARN polimerasa Antituberculoso esterilizante más potente
Bactericida intra y extra celular

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5
Q

rifampicina ADME

A

permeabilidad al SNC (tuberculosis meníngea)

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6
Q

rifampicina EA

A

hepatotoxicidad
liquidos del cuerpo naranjas
resistencia
hipersensibilidad

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7
Q

etambutamol

A

bloqueando la arabinosiltransferasa, que sintetiza el arabinogalactán que utiliza la pared celular bacteriana

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8
Q

etambutamol EA

A

Neuritis óptica,
alteración de la visión (rojo y verde)
Hiperuricemia y gota

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9
Q

Pirazinamida EA

A

Inhibe la sintasa de ácidos grasos de las micobacterias, que es una enzima que también participa en la síntesis del ácido micólico.

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10
Q

Pirazinamida EA

A

Artralgias, hiperuricemia y gota

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