Dislipedeamia Flashcards
what is a lipid
organic molecule, poorly souble in water
carbon containing, few oxygen molecules
hygrophilic head, hydrophobic tail
what is a TAG
3 FA attached to a glycerol
less O2
more hydrophobic
what is cholestrol ester (CE)
cholestrol and FA
no oxygen
why do we need fat
energy cell membrane protection of organs thermal insulation neural insulation
why do we need cholestrol
acts as a membrane stiffner present between TAG tails uses in - steriods - vit D - bile acid
what is the role of lipoproteins
make cholestrol and TAG souble
has a hydrophobic core made up of TAG and cholestrol
hydrophilic outside
what is the only way the body can get rid of cholestrol
through excretion
name the 4 lipoproteins
chylomicrons
VLDL
LDL
HDL
describe chylomicrons in terms of lipid, protein and density
high lipid
low protein
low density
describe VLDL in terms of lipid, protein and density
high ish density
lowish protein
low ish lipid
describe LDL in terms of lipid, protein and density
low ish lipid
highish protein
highish density
describe HDL in terms of lipid, protein and density
high protein
low lipid
high density
how do short and medium chain Fats enter the blood
TAG and CE broken down in FA and glycerol in the intestinal lumen
enter portal vien
Postprandial
what does HDL donate to Chylomicron
Apo protein C2 and Apo E
Postprandial
how does the chylomicron bind to the tissue
via Apo C2 and lipoprotein lipase
TAG absorbed
Postprandial
what is produced after chylomicron binds
a chylomicron remant
more cholestrol dense, less TAG
Postprandial
what happens to the chylomicron remant
ApoC2 goes back to HDL
ApoE binds to receptor on liver
chlyomicron remnant stored in liver
Fasted
how much of the VLDL remant bind to the liver
50%