Diseases Of The Digestive System Flashcards
What is the main route for digestive system ?
Fecal - oral
What does it mean fecal to oral route?
Contaminated food and water
What is the prevention of fecal to oral rote?
Good sewage treatment
Disinfection of drinking water
Proper food handling
Majority of infection that effect the digestive system will effect what organ?
Large intestine
What are the 5 bacterial disease of the digestive system?
( S, SA, T, C, E )
Staphylococcal food poisoning
Salmonella
Typhoid fever
Cholera
Travelers diaherra ( E. coli gastroenteritis )
What are the viral diseases for the digestive system?
Hepatitis
What does food infection mean? And becomes what
Pathogen enters the GI tract and multiples
( microbe stay in GI and become Systemic )
What does food intoxication or food poisoning mean?
And symptoms are due to what?
Ingestion of an exotoxin
( symptoms are due to the toxin not the microbe )
What does gastroenteritis mean?
Inflammation of stomach and intestinal mucosa
What are the common symptoms of digestive diseases?
Diarrhea
Abdominal cramps
Nausea & vomiting
What is the disease of the pre formed exotoxin that causes food intoxication?
( that we learned before this )
Adult botulism
What is staphylococcus aureus?
( staining, shape and grows)
Positive
Coccus
Clusters
Staphylococcus aureus is mainly known for its?
( in digestive sense )
Food poisoning
What causes the food poisoning in staphylococcus aureus?
Ingestion if pre formed exotoxin
Where are these exotoxins found in? What part of the body?
Nasal passages & skin lesions
Can staphylococcus aureus tolerate high salt, organic compound and high temperature?
Yes
Where does staphylococcus aureus grow on to cause food poisoning?
Grows on food
What are the symptoms of staphylococcus aureus?
Diaherria
Stomach pain
Can staphylococcus aureus go away within 24 hours in healthy people?
Yes
Once staphylococcus aureus is ingested, the preformed exotoxin is secreted and also known as ?
Enterotoxin
What type of foods is staphylococcus aureus mainly known for?
Potato salad
Mayonnaise
Tuna fish
( creamy foods )
What is a prevention for staphylococcus aureus?
Boil for 30mins to inactive toxin
Will you get sick if you eat the staphylococcus aureus microbe?
No
Will you get sick if you eat the preformed exotoxin of staphylococcus aureus?
Yes
Exotoxin is a what?
Protein
What is salmonella?
( shape and stain?)
Gram negative
Rod
Where is salmonella found in?
Intestines of animals
( mainly poultry eggs )
What is the bacteria that causes salmonellosis?
Salmonella enteritica
What does the cell surface Antigen on a salmonella Enterica tell us? And what are 2 antigens ?
Different species
VI - capsule
H - flagella
How long is the food infection for salmonella Enterica?
12-36 hours
What are the symptoms of salmonella enteritica ?
Fever nausea vomiting
What are the 3 steps of how salmonella enteritica goes in the body?
- Enters epithelial cells
- Multiples in vesicle
- Inflammatoryresponse
Can salmonella go on it’s own, and how?
Yes within a few days
Main key is hydration
Is there a need for salmonella entertica to have antibiotics?
Nah, it’ll go away on its own
Is salmonella Enterica zoonotic?
Yes
What is typhoid fever bacteria?
Salmonella typhi
What is salmonella Typhi
( gram stain and shape?)
Negative
Rod
Is salmonella Typhi, or typhoid fever only a human pathogen?
Yes
What are the virulence factors of thyroid fever?
Endotoxins
What is the transmission of typhoid fever?
Oral to fecal
What are the symptoms of typhoid fever?
Fever, rose spots and diaherria later on
What makes typhoid fever symptoms so scary?
Internal bleeding
( perforation of intestinal wall )
What is the treatment for typhoid fever?
Antibiotics
What are the carriers of typhoid fever?
( Typhoid Mary )
Food handlers and found in gallbladder (1-3%)
What are the 4 F’s in typhoid fever stand for?
Feces
Flies
Fingers
Food
What is the prevention of typhoid fever?
Hand washing
Clean sewage
What is the vaccine for typhoid fever? (2)
Subunit and live oral vaccine
When do we mainly give out the typhoid vaccine?
Usually to traveling to places where typhoid fever is endemic
What is the bacteria for cholera?
Vibrio cholera
What is vibrio cholera
( stain, shape)
Negative
Rod
What is are two major characteristics of cholera?
Comma shape
High ph
What is cholera transmission?
Oral to fecal
Are humans the only reservoirs for cholera?
Yes
How do we get cholera?
Contaminated water and undercooked seafood
What does cholera do in the body?
Adheres to the intestinal lining and produces an exotoxin
What is cholera exotoxin?
Choleragen
What is choleragen (enterotoxin) do?
Increases C amp
What are the symptoms of cholera?
“Rice water” watery diaherra
What is the treatment of cholera?
Drinking water and replacing electrolytes
What is the prevention of cholera?
Good water and cooking seafood properly
What is the vaccine for cholera? Given what?
Killed cell vaccine
( oral )
What are some methods to help reduce the risk of cholera?
Boiling water
Life straws
What is e. Coli gastrroenteitis ?
Travelers diaherra
What is E. coli?
( stain, shape, anaerobic or aerobe?)
Negative
Rod
Facultative anaerobic
What is E. coli mainly associated with?
Travels diaherria
How do you get travers diaherria ?
Drinking water that you’re not use to
What is the E. coli under travels diarrhea?
Enterotoxigenic E. coli
Enterotoxigenic E. coli is what symptoms and can be cured by?
Watery diarrhea
Hydration
What is enterohemorrgaic E. coli (0157 H7 )
Bloody diarrhea
Where do you mainly find Enterohemorrhagic E. coli (0157 H7)
Cattle
What are some examples of things that can potentially give you enterohemorrhagic E. coli (0157 H7)?
Undercook hamburgers
Lettuce
Spinach
Is enterhemorrhagic E. coli deadlier than Enterotoxigenic E. coli?
Yes
Why is E. coli 0157 H7 so deadly?
Caused kidney failure in young kids, elderly and immunodeficiency
E. coli 0157 H7 caused what syndrome in the immuno, kids and elders?
Uremic syndrome -> kidney failure
What is hepatitis?
Inflammation of the liver
What is the major symptom of hepatitis ? And is caused by
Jaundice
( make yellow of skin and eyes )
Caused by the bilirubin in the liver
What is hepatitis A?
( family, naked or enveloped, shape, single or double, rna or dna ?)
Piconarvidiae
Naked
Isosahedral
Single
Rna
What is hepatitis A transmission?
Oral to fecal
( contaminated water )
What is hepatitis A symptoms?
Fever headache jaundice
Is hepatitis A chronic?
Nope
Does hepatitis A have a vaccine ? And what is it
Yes
Killer vaccine in 2 doses
What is hepatitis B?
( family, enveloped or naked, shape. double or single, dna or rna ?)
Hepadnarviridae
Enveloped
Isosahedral
Double
Dna
What is the transmission of hepatitis B?
Sex, blood, needles, mother to baby
What are the symptoms of hepatitis B?
Fever
Joint pain
Jaundice
Is hepatitis chronic and caused what?
Yes 10%
Liver cancer
What is hepaticellular caricinoma mean?
Liver cancer
What is the treatment for hepatitis B? ( AI)
Alpha interferon
What is the prevention/vaccine for hepatitis B?
Recombinant subunit vaccine
When do we normally give out the vaccine for hepatitis B?
The second we are born pretty much
What is hepatitis C
( family, Enveloped or naked, shape, single or double, rna or dna ?)
Flaviviridae
Enveloped
Isosahedral
Single
Rna
What is hepatitis C transmission?
Blood, needles, tattoos
How chronic is hepatitis C and caused what?
50%
Liver cancer
What are symptoms for hepatitis C?
Usually more milder fever than others
What is the treatment for hepatitis C?
Drugs for 2-3 months to cure it
( however really expensive )
Is there a vaccine for hepatitis C?
No
What is hepatitis D?
( enveloped or non, rna or dna, what type of agent?)
Envelope
Rna
Defective agent
What is hepatitis D transmission?
Comes from having Hepatitis B ( bodily fluids )
What does defective agent mean for hepatitis D?
Has to have hepatitis B in order to replicate
What are hepatitis D symptoms?
Intensified HBV
Can we prevent hepatitis D?
Yes through the vaccine of HBV ; subunit
What is hepatitis E
( family, single or double, naked or Enveloped or rna or dna ?)
Caliciviridae
Single
Naked
Rna
How is heptiatis E transmitted by?
Oral to fecal
What are the symptoms of hepatitis E?
Similar to hepatitis A
Fever headache
Is there a vaccine for hepatitis E?
No
What is the morality rate of hepatitis E? Adult and pregnant women?
Adult - 1%
Pregnant women- 20%