Disease Of The Cardiovascular & Lymphatic System Flashcards
What are main things to look out for that effect the cardio and lympathtic system?
Vessels
&
Major organs
What does septicemia mean?
Acute illness due to the presence of pathogens or their toxins in the blood
What does sepsis mean?
( SIRS )
Systemic inflammatory responses syndrome
( SIRS )
What does lymphangitis mean?
Inflamed lymph vessels
What does severe sepsis mean?
Decreased blood pressure and dysfunction of at least one organ
What does septic shock mean?
Sepsis and uncontrollable decreased blood pressure
What are the 3 bacterial disease we will be looking at in cardio & lymphatic system?
Plague
Lyme disease
Rocky Mountain spotted fever
What are the 1 viral cardio vascular & lympathic disease ?
Ebola hemorrhagic fever
What is the one protozoal disease of the cardiovascular & lymphatic system?
Malaria
What is another name for the plague?(2)
Black Death and or bubonic plague
What is the bacteria that causes the plague?
Yersinia Pestis
What is Yersinia Pestis?
( stain and shape?)
Gran negative
Rod
What is the transmission of Yersinia Pestis ( black plague ?)
Fleas and rats
What did the plague infect?
Rats, dogs, chipmunks
Later into humans
Humans are what type of host for the plague ?
Incidental host
What are the virulence factors for the plague?(3)
( c, e, AG )
Capsule
Endotoxin
2 sirfsce antigens that resists phagocytosis
The plague is what type of disease? (2)
Zoonotic and vector
What is a good indicator that one has the plague?
Buboes
What is buboes?
Swollen lymph nodes of groin and armpit
How does the body get this swollen lymph nodes (4)? Steps ?
Flea gets infected blood from rat
Flea goes crazy & bites humans
Goes into human blood
Swollen lymph nodes
What was the mortality rate of the plague?
50-75%
What does septicemic plague mean?
Bacteria leaves lymphatics and enter blood, causes death
What does pneumonic plague mean?
Bacteria is inhaled and enter lung -> death
What is the prevention of plague?
Killing fleas
Is there a vaccine for the plague? Name and what is it?
Killed vaccine
Y. Pestis
What is Lyme disease? Bacteria?
Borrelia burgforferi
What is borrelia burgforferi?
( shape )
Spirochetes
( helical & axial filaments )
Is Lyme disease a vector and zoonotic disease?
Yes
What causes Lyme disease vs what Carried it?
Causes - borrelia burgdorferi
Carries - ticks
What are the reservoirs for Lyme disease?
Mouse & deer
What are the symptoms of Lyme disease? It also has erythema migrants, what is that?
Bulls eye rash
Flu like symptoms
Irregular heartbeat & encephalitis
Arthritis
Erythema migrants
- middle to out of the skin
What is the primary symptoms of Lyme disease?
Bull eye rash
What is the second phase of Lyme disease?
Irregular heart beat & encephalitis
What is the third phase of Lyme disease?
Arthritis
When is the best time to treat Lyme disease?
When we see the bull eye rash
What do we give to someone who is having Lyme disease?
Antibiotics
Is there a vaccine for Lyme disease?
No
What bacteria causes Rocky Mountain spotted fever ?
Rickettsia rickettsia
What is rickettsia rickettsia?
Obligate intracellular parasite
How is rickettsia transmitted by?
Ticks
Where do we mainly find rocket mountain spotted fever?
In the apla. mountains
What are the symptoms (rashes name ) of rickettsia rickettsia? And when do they occur?
2 week
Hemmorrahagic rashes
What does it mean hemmorrhagic rashes?
Pins or needles poked the skin
Where does these hemmorrhagic rashes appear on the body?
Palms and soles of the feet
What is the treatment of Rocky Mountain spotted fever?
Antibiotics
Is there a vaccine for Rocky Mountain spotted fever?
Nope
What is Ebola hemorrhagic fever
( family, negative or positive, enveloped or non, single or double, rna or dna )
Filoviridae
Negative
Enveloped
Single
Rna
What is the transmission of Ebola?
Contact with blood or bodily fluids of infected
Is Ebola transmitted by air, water or food?
NO
What is the symptoms of Ebola?
Fever, vommitting
Macular rash
Hemorrhaging
Is there a vaccine for Ebola?
No
Is there treatment for Ebola? What is it?
Yes
Supportive therapy or blood transfusion
What is the prevention of Ebola?
PPE !!
What is malaria caused by?
A PROTOZOAN
What is a protozoan?
Eukaryotic
What is the protozoan that causes malaria?
Plasmodium Sp
What are the 4 types of plasmodium?
Vivax
Malariae
Ovale
Falciparium
What is the most common plasmodium that causes malaria?
Plasmodium falciparum
What is the transmission of malaria?
Mosquitoes
( anopheles)
How does malaria get into the body? 3 steps?
Blood -> liver -> infects RBC ( lyses )
What are the symptoms of malaria? When do they mainly occur?
Mainly occur at night
Fever, chills, sweats, Nausea
What is the main symptom distinction of malaria?
Cyclic episodes
( recover and recur 2-3 days interval )
Is there a vaccine? What is it
Yes but not fully “ready”
Subunit vaccine
What are the 3 deadliest diseases?
Malaria
HIV
TB
The most common cause of bacterial throat infection ( pharyngitis)
- staphylococcus
- streptococcus
- mycobacterium
- diptheria
Streptococcus
( strep throat )
What causes Malaria vs carried it?
Causes - plasmodium ( protozoan )
Carries - mosquitos