Diseases of Salivary Glands- Non-neoplastic

Question 1

The parotid gland is mostly composed of:

Answer 1

serous acinar cells

Question 2

What type of cells can be seen in this image? What gland is this?

Answer 2

serous acinar cells; parotid gland

Question 3

What may be particularly seen in a histological image of the parotid gland?

Answer 3

fat cells

Question 4

The serous acinar cells of the parotid gland are very ____ because they contain ____

Answer 4

granular; zymogens

Question 5

The _____ gland contains 100% serous acinar cells

Answer 5

parotid

Question 6

The submandibular gland is a _____ gland

Answer 6

seromucous

Question 7

This stain is highlighting the mucous acinar cells in red. What gland can be seen here?

Answer 7

submandibular

Question 8

The sublingual gland is comprised of ____ & ____ acinar cells but is mostly ____.

Answer 8

mucous & serous; mucous

Question 9

The histological slide on the right shows many mucous acinar cells. What gland is seen? What cells are stained red? What cells are stained brown?

Answer 9

sublingual
red= mucous acinar cells
brown= serous acinar cells

Question 10

Two locations in which we see a lot of minor salivary glands:

Answer 10

palate & retromolar pad

Question 11

• minor salivary gland
• Circumvalate papillae
• Serous acinar

Answer 11

Glands of Von ebner

Question 12

• minor salivary gland
• foliate papillae
• mucous acinar

Answer 12

Glands of Weber

Question 13

-minor salivary gland
- anterior ventral
- mucous acinar

Answer 13

Glands of Blandin and Nunn

Question 14

Disruption in ductal system that causes mucous to get trapped inside the connective tissue forming a little balloon or bubble:

Answer 14

mucocele (mucous extravasation reaction)

Question 15

This patient has a history of trauma (biting their lip), resulting in this bluish abnormality. What is the likely diagnosis?

Answer 15

mucocele

Question 16

This is a mucocele occurring on the bottom side of the tongue. What glands are involved?

Answer 16

Glands of Blandin & Nunn

Question 17

What can be seen in this histological slide? Pt experience trauma prior to coming in.

Answer 17

mucocele (granulation tissue trying to wall off)

Question 18

Common place to find superficial mucoceles

Answer 18

palate

Question 19

What can be seen in this image?

Answer 19

superficial mucoceles

Question 20

special type of mucocele associated with the sublingual gland.

Answer 20

ranula

Question 21

When mucin dissects through the mylohyoid muscle presenting as a neck mass:

Answer 21

plunging ranula

Question 22

Mucin that gets trapped in the salivary ductal system causing the mucin to calcify

Answer 22

Sialolith (salivary stone)

Question 23

The ductal system that is most commonly affected by sialoliths:

Answer 23

Wharton’s gland

Question 24

Patient comes in complaining of episodic swelling, particularly around meal times, and experiences pain due to this. This is a sign of:

Answer 24

sialolith (no way for saliva to flow through dural system because its blocked by a stone resulting in swelling)

Question 25

Patient presents with this, and you note it is very hard on palpation. What is the diagnosis and what gland is this associated with?

Answer 25

sialolith; Wharton’s duct

Question 26

What type of radiograph would you order if you suspect a sialolith in wharton’s duct?

Answer 26

occlusal radiograph

Question 27

necrotizing sialometaplasia can be described as:

Answer 27

a completely reactive condition

Question 28

A patient comes in and states a piece of the roof of their mouth plopped out. With only this info what would be your diagnosis?

Answer 28

necrotizing sialometaplasia

Question 29

Patient comes in with bilateralateral areas of ulceration on the roof of their mouth. What is the diagnosis?

Answer 29

necrotizing sialometaplasia

Question 30

histologically appears as if the epithelium is pinching off at the surface going into the connective tissue but is NOT cancerous (pseudoepitheliomatous hyperplasia)

Answer 30

necrotizing sialometaplasia

Question 31

-pseudoepitheliomatous hyperplasia
- coagulative necrosis of the gland
- sialometaplasia

histologically, these may all represent:

Answer 31

necrotizing sialometaplasia

Question 32

This histological slide shows squamous metaplasia of the salivary gland tissue; what is this characteristic of?

Answer 32

necrotizing sialometaplasia

Question 33

Your patient comes in with extremely dry mouth and dry eyes, and remembers they were diagnosed with an autoimmune disorder but doesn’t recall which one. What condition might they have and what does this affect?

Answer 33

Sjogrens syndrome; salivary gland tissue

Question 34

Sjogren syndrome in which there is NOT another diagnosis of an additional autoimmune disease

Answer 34

Primary

Question 35

Sjogren syndrome + additional diagnosis of another autoimmune disease

Answer 35

secondary

Question 36

Patient presents with bilateral enlargement of the parotid gland. You perform a biopsy and this reveals BLEL (benign lymphoepithelial lesion which is also known as Mikulicz’s disease). What is your diagnosis?

Answer 36

Sjogrens syndrome

Question 37

How can you diagnose Sjögren’s syndrome through laboratory values? List the values specific to Sjogren syndrome. List values non-specific to sjogrens syndrome:

Answer 37

Specific:
Anti-SSa
Anti-SSb

Non-specific
RF
ANA

Question 38

This patient presents with assymetrical enlargement of the parotid gland. What is the likely diagnosis?

Answer 38

Sjogren’s Syndrome

Question 39

Pt presents with dry mouth and dry eyes, as well as bilateral asymmetrical enlargement of the parotid gland. What is a probable diagnosis for this?

Answer 39

Sjogren Syndrome

Question 40

Anti-SS-A may also be known as:

Anti-SS-B may also be known as:

These are laboratory values for:

Answer 40

Anti-Ro
Anti-La

Sjorgren syndrome

Question 41

This image shows asymmetrical enlargement of the parotid gland. What is this characteristic of?

Answer 41

Sjogren syndrome

Question 42

Whenever you have a systemic disease that effects the major glands this is also:

Give an example of when this occurs:

Answer 42

Mimics in the minor glands; Sjogrens syndrome

Question 43

You perform a lower lip biopsy and find lymphoid clusters. The acinar cells have been completely destroyed and there are remnants of the ducts. There is a high number of the clusters and destroyed acinar cells. What is your diagnosis?

Answer 43

Sjogren syndrome

Question 44

Pt presents with
- dry mouth
- dry eyes
- mouth sticks to tongue depressor
- rampant caries

Diagnosis?

Answer 44

Sjogren syndrome