Diseases of Salivary Glands- Non-neoplastic Flashcards
The parotid gland is mostly composed of:
serous acinar cells
What type of cells can be seen in this image? What gland is this?
serous acinar cells; parotid gland
What may be particularly seen in a histological image of the parotid gland?
fat cells
The serous acinar cells of the parotid gland are very ____ because they contain ____
granular; zymogens
The _____ gland contains 100% serous acinar cells
parotid
The submandibular gland is a _____ gland
seromucous
This stain is highlighting the mucous acinar cells in red. What gland can be seen here?
submandibular
The sublingual gland is comprised of ____ & ____ acinar cells but is mostly ____.
mucous & serous; mucous
The histological slide on the right shows many mucous acinar cells. What gland is seen? What cells are stained red? What cells are stained brown?
sublingual
red= mucous acinar cells
brown= serous acinar cells
Two locations in which we see a lot of minor salivary glands:
palate & retromolar pad
- minor salivary gland
- Circumvalate papillae
- Serous acinar
Glands of Von ebner
- minor salivary gland
- foliate papillae
- mucous acinar
Glands of Weber
-minor salivary gland
- anterior ventral
- mucous acinar
Glands of Blandin and Nunn
Disruption in ductal system that causes mucous to get trapped inside the connective tissue forming a little balloon or bubble:
mucocele (mucous extravasation reaction)
This patient has a history of trauma (biting their lip), resulting in this bluish abnormality. What is the likely diagnosis?
mucocele
This is a mucocele occurring on the bottom side of the tongue. What glands are involved?
Glands of Blandin & Nunn
What can be seen in this histological slide? Pt experience trauma prior to coming in.
mucocele (granulation tissue trying to wall off)
Common place to find superficial mucoceles
palate
What can be seen in this image?
superficial mucoceles
special type of mucocele associated with the sublingual gland.
ranula
When mucin dissects through the mylohyoid muscle presenting as a neck mass:
plunging ranula
Mucin that gets trapped in the salivary ductal system causing the mucin to calcify
Sialolith (salivary stone)
The ductal system that is most commonly affected by sialoliths:
Wharton’s gland
Patient comes in complaining of episodic swelling, particularly around meal times, and experiences pain due to this. This is a sign of:
sialolith (no way for saliva to flow through dural system because its blocked by a stone resulting in swelling)
Patient presents with this, and you note it is very hard on palpation. What is the diagnosis and what gland is this associated with?
sialolith; Wharton’s duct
What type of radiograph would you order if you suspect a sialolith in wharton’s duct?
occlusal radiograph
necrotizing sialometaplasia can be described as:
a completely reactive condition
A patient comes in and states a piece of the roof of their mouth plopped out. With only this info what would be your diagnosis?
necrotizing sialometaplasia
Patient comes in with bilateralateral areas of ulceration on the roof of their mouth. What is the diagnosis?
necrotizing sialometaplasia
histologically appears as if the epithelium is pinching off at the surface going into the connective tissue but is NOT cancerous (pseudoepitheliomatous hyperplasia)
necrotizing sialometaplasia
-pseudoepitheliomatous hyperplasia
- coagulative necrosis of the gland
- sialometaplasia
histologically, these may all represent:
necrotizing sialometaplasia
This histological slide shows squamous metaplasia of the salivary gland tissue; what is this characteristic of?
necrotizing sialometaplasia
Your patient comes in with extremely dry mouth and dry eyes, and remembers they were diagnosed with an autoimmune disorder but doesn’t recall which one. What condition might they have and what does this affect?
Sjogrens syndrome; salivary gland tissue
Sjogren syndrome in which there is NOT another diagnosis of an additional autoimmune disease
Primary
Sjogren syndrome + additional diagnosis of another autoimmune disease
secondary
Patient presents with bilateral enlargement of the parotid gland. You perform a biopsy and this reveals BLEL (benign lymphoepithelial lesion which is also known as Mikulicz’s disease). What is your diagnosis?
Sjogrens syndrome
How can you diagnose Sjögren’s syndrome through laboratory values? List the values specific to Sjogren syndrome. List values non-specific to sjogrens syndrome:
Specific:
Anti-SSa
Anti-SSb
Non-specific
RF
ANA
This patient presents with assymetrical enlargement of the parotid gland. What is the likely diagnosis?
Sjogren’s Syndrome
Pt presents with dry mouth and dry eyes, as well as bilateral asymmetrical enlargement of the parotid gland. What is a probable diagnosis for this?
Sjogren Syndrome
Anti-SS-A may also be known as:
Anti-SS-B may also be known as:
These are laboratory values for:
Anti-Ro
Anti-La
Sjorgren syndrome
This image shows asymmetrical enlargement of the parotid gland. What is this characteristic of?
Sjogren syndrome
Whenever you have a systemic disease that effects the major glands this is also:
Give an example of when this occurs:
Mimics in the minor glands; Sjogrens syndrome
You perform a lower lip biopsy and find lymphoid clusters. The acinar cells have been completely destroyed and there are remnants of the ducts. There is a high number of the clusters and destroyed acinar cells. What is your diagnosis?
Sjogren syndrome
Pt presents with
- dry mouth
- dry eyes
- mouth sticks to tongue depressor
- rampant caries
Diagnosis?
Sjogren syndrome
