Diseases of Salivary Glands- Malignant

Question 1

List the malignant salivary gland tumors:

Answer 1

1. mucoepidermoid carcinoma
2. adenoid cystic carcinoma
3. polymorphous low-grade adenocarciomma
4. acidic cell carcinoma
5. carcinoma ex-mixed tumor
6. adenocarcinoma NOS

Question 2

• Most common malignant salivary gland neoplasm
• Occurs in middle-aged females
• Clinically mistaken for a mucocele

Answer 2

mucoepidermoid carcinoma

Question 3

What malignant salivary gland neoplasm is clinically mistaken for a mucocele?

Answer 3

Mucoepidermoid carcinoma

Question 4

Patient presents with a palatal swelling with some redness and a small point of the start of ulceration. It looks very similar to a mucocele. What is a potential diagnosis?

Answer 4

mucoepidermoid carcinoma

Question 5

Diagnose what is seen on the lower lip, The patient states that it is painful and you see a small point of ulceration. What is a differential diagnosis for this?

Answer 5

Mucoepidermoid carcinoma; mucocele

Question 6

We often don’t see salivary gland neoplasms associated with the lower lip, but IF WE DO, it is most likely:

Answer 6

mucoepidermoid carcinoma

Question 7

What malignant tumor presents histologically with:

• mucous producing cells
• epidermoid (squamous) cells
• may be cystic or solid

Answer 7

mucoepidermoid carcinoma

Question 8

Because it is very hard to differentiate between a high grade mucoepidermoid carcinoma and squamous cell carcinoma, what staining method may be beneficial for diagnosis?

Answer 8

mucicarmine

Question 9

• BEST recognized salivary gland tumor
• middle-aged females
• slow growing mass
• painful
• malignant

Answer 9

adenoid cystic carcinoma

Question 10

Pt presents with a malignant tumor of the tongue. This is not common, What is the most likely diagnosis?

Answer 10

adenoid cystic carcinoma

Question 11

What malignant tumor presents histologically with:

• myoepithelial and ductal cells
• perineural and perivascular invasion (contributes to poor prognosis)
• cribriform patter
• Swiss cheese

Answer 11

adenoid cystic carcinoma

Question 12

What contribtures to the very poor prognosis of adenoid cystic carcinoma?

Answer 12

perineural and perivascular invasion

Question 13

• Most common malignant MINOR salivary gland neoplasm
• middle-aged females
• favors palate

Answer 13

polymorphous low-grade adenocarcinoma

Question 14

If we see a tumor of the retromolar pad, it is most likely going to be:

Answer 14

malignant (mucoepidermoid carcinoma)

Question 15

What malignant tumor presents histologically with:

• deceptive uniform appearance
• different growth patterns
• perineural & perivascular invasion
• indian filing

Answer 15

PLGA

Question 16

In this histological image, we can see this Indian filing pattern due to perivascular invasion. What is the diagnosis?

Answer 16

PLGA

Question 17

• Parotid gland
• serous acinar differentiation
• middle-aged females
• slow growin
• low-grade malignancy

Answer 17

acidic cell carcinoma

Question 18

What malignant tumor presents histologically with:

• well circumscribed
• may be infiltrative
• serous acinar cell (abundant granular basophilic cytoplasm and a round, stain eccentric nucleus)

Answer 18

acidic cell carcinoma

Question 19

• long standing pleomorphic adenoma
• older adults
• rapid growth
• pain & ulceration

Answer 19

carcinoma ex- pleomorphic adenoma

Question 20

Patient initially had a pleomorphic adenoma but this was not adequately treated and this condition worsened, and is now accompanied by pain & ulceration. Diagnosis?

Answer 20

carcinoma ex-pleomorphic adenoma

Question 21

What malignant tumor presents histologically with:

• typical benign mixed tumor
• malignant degeneration
• cellular pleomorphism
• abnormal mitotic activity
• capsular invasion

Answer 21

carcinoma ex-pleomorphic adenoma

Question 22

• uncommon salivary gland neoplasm
• cannot be calssified
• middle-aged females

Answer 22

Adenocarcinoma NOS