Diseases of Salivary Glands- Malignant Flashcards
List the malignant salivary gland tumors:
- mucoepidermoid carcinoma
- adenoid cystic carcinoma
- polymorphous low-grade adenocarciomma
- acidic cell carcinoma
- carcinoma ex-mixed tumor
- adenocarcinoma NOS
- Most common malignant salivary gland neoplasm
- Occurs in middle-aged females
- Clinically mistaken for a mucocele
mucoepidermoid carcinoma
What malignant salivary gland neoplasm is clinically mistaken for a mucocele?
Mucoepidermoid carcinoma
Patient presents with a palatal swelling with some redness and a small point of the start of ulceration. It looks very similar to a mucocele. What is a potential diagnosis?
mucoepidermoid carcinoma
Diagnose what is seen on the lower lip, The patient states that it is painful and you see a small point of ulceration. What is a differential diagnosis for this?
Mucoepidermoid carcinoma; mucocele
We often don’t see salivary gland neoplasms associated with the lower lip, but IF WE DO, it is most likely:
mucoepidermoid carcinoma
What malignant tumor presents histologically with:
- mucous producing cells
- epidermoid (squamous) cells
- may be cystic or solid
mucoepidermoid carcinoma
Because it is very hard to differentiate between a high grade mucoepidermoid carcinoma and squamous cell carcinoma, what staining method may be beneficial for diagnosis?
mucicarmine
- BEST recognized salivary gland tumor
- middle-aged females
- slow growing mass
- painful
- malignant
adenoid cystic carcinoma
Pt presents with a malignant tumor of the tongue. This is not common, What is the most likely diagnosis?
adenoid cystic carcinoma
What malignant tumor presents histologically with:
- myoepithelial and ductal cells
- perineural and perivascular invasion (contributes to poor prognosis)
- cribriform patter
- Swiss cheese
adenoid cystic carcinoma
What contribtures to the very poor prognosis of adenoid cystic carcinoma?
perineural and perivascular invasion
- Most common malignant MINOR salivary gland neoplasm
- middle-aged females
- favors palate
polymorphous low-grade adenocarcinoma
If we see a tumor of the retromolar pad, it is most likely going to be:
malignant (mucoepidermoid carcinoma)
What malignant tumor presents histologically with:
- deceptive uniform appearance
- different growth patterns
- perineural & perivascular invasion
- indian filing
PLGA
In this histological image, we can see this Indian filing pattern due to perivascular invasion. What is the diagnosis?
PLGA
- Parotid gland
- serous acinar differentiation
- middle-aged females
- slow growin
- low-grade malignancy
acidic cell carcinoma
What malignant tumor presents histologically with:
- well circumscribed
- may be infiltrative
- serous acinar cell (abundant granular basophilic cytoplasm and a round, stain eccentric nucleus)
acidic cell carcinoma
- long standing pleomorphic adenoma
- older adults
- rapid growth
- pain & ulceration
carcinoma ex- pleomorphic adenoma
Patient initially had a pleomorphic adenoma but this was not adequately treated and this condition worsened, and is now accompanied by pain & ulceration. Diagnosis?
carcinoma ex-pleomorphic adenoma
What malignant tumor presents histologically with:
- typical benign mixed tumor
- malignant degeneration
- cellular pleomorphism
- abnormal mitotic activity
- capsular invasion
carcinoma ex-pleomorphic adenoma
- uncommon salivary gland neoplasm
- cannot be calssified
- middle-aged females
Adenocarcinoma NOS
