diseases

Question 1

Where does breast cancer originates

Answer 1

from mammary glands

Question 2

What happens to the mucus in cystic fibrosis? Where does this happens?

Answer 2

becomes thicker and harder to get out.

- happens both in the respiratory and in the pancreas

Question 3

poor wound healing

Answer 3

dense regular CT

Question 4

crosslinks between hydroxylysine and hydroxyproline are not good

Answer 4

Scurvy

Question 5

defect lies in collagen synthesis leading to CT disorder

Answer 5

Ehler-Danlos

Question 6

abnormal accumulations of collagen

Answer 6

keloids

Question 7

mut. in fibrillin-1

Answer 7

marfan

Question 8

condition characterized by inflammation of joints due to degeneration of articular cartilage

Answer 8

arthritis

Question 9

disease of aging and caused by “wear and tear” of the articular cartilage

Answer 9

osteoarthritis

Question 10

autoimmune disease involving cartilage, bone and synovial membranes

Answer 10

rheumatoid arthritis

Question 11

brittle bone disease

Answer 11

Osteogenesis imperfecta

Question 12

mutation in collagen I

Answer 12

Osteogenesis imperfecta

Question 13

bone resorption>bone formation

Answer 13

osteoporosis

Question 14

accelerated remodeling of bone leads to deposition and accumulation of woven bone. both woven and lamellar bone appear to give a mosaic appearance

Answer 14

Paget’s disease

Question 15

smooth muscle tumors almost exclusively found in the uterus

Answer 15

Leiomyomas

Question 16

regeneration in the PNS is blocked because after injury a glial scar is formed over the injury which is a tangled mesh of astrocytes preventing nerve growth

Answer 16

Wallerian Degeneration

Question 17

dystrophin deficiency leads to mechanical failure and hypercalcemia (increased osmosis and mitochondrial rupture)

Answer 17

Muscular Dystrophy