Diseases Flashcards
Epidemic
occurrence of a disease in a community or region that is more than normal
Endemic
when a disease is expected to be around to some degree within a geographical area. e.g. plague
Communicable diseases are those that are transferable from one _______ to another
from one host to another
Epidemiology is the study of _______
diseases
Pandemic
a disease that exists throughout a wide area
Zoonosis is a group of ____________ diseases that can be transmitted to ______. e.g. is __________
animal diseases transferable to man.
e.g. rabies
Acute vs. Chronic diseases
acute - rapid onset
chronic - prolonged exposure, long duration illness
Direct vs. Indirect transmission of diseases
direct - human to human, animal to human, animal to animal
indirect - vector, fomites
bacteria are usually ___ to ____ microns in size
.5 to 3 microns
Name 4 common bacterial shapes
rod, cocci, clumps, spiral
clinical vs carrier casses
clinical - symptomatic
carrier - asymptomatic (typhoid mary)
subclinical is the state of the host (before/after) the disease causes symptoms
before symptoms
the vehicle is how the infectious agent gets transmitted to the host.
e.g. are____ and _____
food and water
What are the 5 routes of infections. Which are the two most common.
respiratory - most common oral/digestive - second most common skin eyes injections
Passive vs. Active immunity and Natural and Acquired forms of both.
Passive - received from another source
naturally passive - maternal transfer
acquired passive - inoculation of antibodies
Active - formed by body’s immune system
naturally active - from infection
acquired active - inoculation by killed virus/agent then body builds immunity
Intrinsic vs. extrinsic host factors
intrinsic (genetic) - age, sex, race, immunologic state
extrinsic (controllable) - personal habits, nutritional state, stress level
synergist/synergy
two chemicals produce a greater effect together than either produce alone
additive effects
two chemicals produce an effect approximately twice that of either chemical alone.
e.g. cigarette smoking and air pollution
multiplicative effects
two chemicals produce an effect several times greater than either product alone
accelerator effect
one chemical enables or enhances the toxic effect of another. similar to a “catalyst.” e.g. soot
Top 4 accidental deaths
car accidents
accidental falls (most common in the home)
fire and explosion (most common in workplace)
accidental drowning
isolation vs quarantine
isolation - disease is know - physical separation to avoid spread
quarantine - disease is unknown
gram stain and colors
gram positive retain crystal violet dye (purple)
gram negative - counter stain (safranin) flushes out the crystal violet - microbes appear (red/pink) thinner cell wall
gram positive bacteria have a thick layer of _____
peptidoglycan
What are the four growth conditions of bacteria in regards to oxygen level
aerobic
microaerophillic - require lower levels of oxygen
facultative anaerobe - will use aerobic respiration but can use anaerobic respiration or fermentation if needed
anaerobic
What are toxins
poisonous substances produced by certain microrgaisms
exotoxins vs endotoxins
exotoxins - secreted by bacteria, a waste product - highly toxic. They are tissue or organ specific. Usually from gram positive.
endotoxins - part of gram negative cell wall called LPS which are released when the bacteria die
What are some of the damaging effects of endotoxins
vasodilation—-> hypotension (low bp)
fever
weakness
leukopenia
the following bacteria produce which types of exotoxins
staph aureus
clost. botulinum
clos. tetani
corneybacterium diptheriae
staph aureus - enterotoxin (GI tract)
clost. botulinum - neurotoxin
clos. tetani - neurotoxin
corneybacterium diptheriae - cytotoxin (attacks living cells)
Colorado Tick Fever type reservoir mode fatality
virus
rodents - squirrels, chipmunks
adult tick - dermacentor andersoni (wood tick)
deaths are rare
________________ is a disease that causes inflammation in parts of the brain, specifically the meninges and spinal cord. This disease is caused by a (bacteria/virus)
Ecephalitis
viral
What are the 4 types of encephalitis that affect humans. Name the mosquito vector(s) for each type
Eastern Equine - Culiseta melanura
St. Louis - Culex tarsalis, Culex pipens
Western Equine - Culex tarsalis
West Nile Virus - Culex tarsalis
In encephalitis, mild cases cane become viral ______________. Sever infections result in disorientation, convulsions and death. Incubation period is between __ and __ days.
mild cases –> viral meningitis
5-15 days incubation
____________ is a viral disease that usually affects the liver giving physical symptoms of jaundice
Hepatitis
What are the three types of hepatitis
Hep A - infectious
Hep B and C - Serum
Hep A type mode average incubation period typical illness duration fatality rate
virus fecal oral route 25-30 days incubation 1-2 week duration low fatality, 1 per 1000
Hep B & C type mode incubation time fatality
virus
blood - hypodermic needles - drug use
60-90 day incubation
1% fatality