Disease List & Clinical Flashcards

1
Q

What does a soft texture of a lymph node indicate?

A

Insignificant

Soft lymph nodes are typically not associated with serious conditions.

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2
Q

What texture of a lymph node is consistent with lymphoma?

A

Rubbery

A rubbery consistency can suggest the presence of lymphoma.

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3
Q

What does a fixed, firm, hard, and nontender lymph node suggest?

A

Malignancy or granulomatous infection

These characteristics often indicate serious underlying pathology.

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4
Q

What does a tender lymph node indicate?

A

Inflammation

Tenderness in lymph nodes is usually associated with inflammatory processes.

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5
Q

What is the lifetime risk of thyroid cancer in men?

A

0.6%

This statistic highlights the relatively low risk for men compared to women.

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6
Q

What is the lifetime risk of thyroid cancer in women?

A

1.8%

Women have a higher risk of developing thyroid cancer compared to men.

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7
Q

What is diffuse enlargement of the thyroid indicative of?

A

Grave’s disease, Hashimoto’s thyroiditis, and endemic goiter

This type of enlargement occurs without the presence of nodules.

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8
Q

What could a single nodule in the thyroid indicate?

A

Cyst, benign tumor, or malignancy

Rapid growth, hardness, or lymphadenopathy increases suspicion for malignancy.

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9
Q

What often causes multinodular goiter?

A

Iodine deficiency

Multinodular goiter is commonly seen in areas with low iodine intake.

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10
Q

What is the consistency of the thyroid in Graves’ disease?

A

Soft, possibly with a bruit

A bruit indicates increased blood flow, commonly associated with hyperthyroid conditions.

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11
Q

What is the consistency of the thyroid in Hashimoto’s thyroiditis?

A

Firm

Firmness in the thyroid can suggest autoimmune conditions like Hashimoto’s.

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12
Q

What are common symptoms of hyperthyroidism?

A
  • Nervousness
  • Weight loss with increased appetite
  • Sweating
  • Heat intolerance
  • Palpitations
  • Frequent bowel movements
  • Muscle weakness
  • Tremor

These symptoms reflect the increased metabolic activity associated with hyperthyroidism.

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13
Q

What are common signs of hyperthyroidism?

A
  • Tachycardia
  • Increased systolic BP
  • Decreased diastolic BP
  • Warm/moist skin
  • Tremor
  • Lid lag
  • Exophthalmos

Signs can help differentiate hyperthyroidism from other conditions.

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14
Q

What are common symptoms of hypothyroidism?

A
  • Fatigue
  • Weight gain
  • Dry skin
  • Cold intolerance
  • Edema
  • Constipation
  • Muscle weakness
  • Memory issues
  • Hearing impairment

These symptoms are indicative of decreased metabolic function.

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15
Q

What are common signs of hypothyroidism?

A
  • Bradycardia
  • Hypothermia
  • Decreased heart sound intensity
  • Coarse skin
  • Non-pitting edema
  • Hair loss
  • Periorbital edema
  • Peripheral neuropathy
  • Somnolence

These signs reflect the body’s response to low thyroid hormone levels.

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16
Q

What does Jugular Venous Distention (JVD) indicate?

A

Heart conditions

Observation for JVD is part of a comprehensive neck exam.

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17
Q

What characteristics are typical of benign thyroid nodules?

A
  • Mobile
  • Soft
  • Without associated lymphadenopathy

These features suggest a lower likelihood of malignancy.

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18
Q

What characteristics are typical of malignant thyroid nodules?

A
  • Hard
  • Fixed
  • Rapidly growing
  • Associated with cervical lymphadenopathy

These signs raise suspicion for thyroid cancer.

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19
Q

What does swelling in posterior auricular and posterior cervical lymph nodes often indicate?

A

Infections or, rarely, malignancies

This type of adenopathy can be a response to localized infections.

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20
Q

What does cervical adenopathy indicate?

A

Infections, inflammatory conditions, or malignancies

Enlargement of cervical lymph nodes can have various underlying causes.

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21
Q

What is Pemberton’s sign?

A

Facial congestion and cyanosis when the arms are raised

This sign indicates compression of the thoracic inlet by a multinodular goiter.

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22
Q

A lymph node that is hard, fixed, and nontender suggests what?

A

Consistent with malignancy or granulomatous infection

This finding is often concerning for serious pathology.

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23
Q

What is the most likely diagnosis for a firm, painless nodule on the thyroid in a patient with a family history of thyroid cancer?

A

Thyroid cancer

Family history and radiation exposure are significant risk factors.

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24
Q

What is the most likely diagnosis for a patient with diffuse thyroid enlargement and no visible nodules?

A

Diffuse thyroid enlargement, possibly due to Graves’ disease

This condition often presents without nodular formation.

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25
Q

What thyroid condition does a soft nodule with a bruit over the lateral lobes most likely indicate?

A

Graves’ disease

The presence of a bruit suggests increased blood flow associated with hyperthyroidism.

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26
Q

What is the most likely diagnosis for a patient with nervousness, weight loss, and a rapid heart rate?

A

Hyperthyroidism

These symptoms are classic for an overactive thyroid.

27
Q

What is the most likely diagnosis for a patient with fatigue, weight gain, and bradycardia?

A

Hypothyroidism

These symptoms indicate a deficiency in thyroid hormone.

28
Q

What does prominent neck veins in a seated upright patient suggest?

A

Jugular Venous Distention (JVD)

This can indicate heart failure or other cardiac issues.

29
Q

What does a hard, fixed thyroid nodule with cervical lymphadenopathy suggest?

A

Consistent with thyroid malignancy

These features raise concerns for cancer.

30
Q

What is the most likely diagnosis for a patient with swollen lymph nodes behind the ear and recent upper respiratory symptoms?

A

Posterior auricular and posterior cervical adenopathy due to infection

This presentation is often seen in viral infections.

31
Q

What is the likely diagnosis for a patient with multiple nodules on the thyroid after returning from an iodine-deficient region?

A

Multinodular goiter due to iodine deficiency

Iodine deficiency is a common cause of goiter.

32
Q

What does facial congestion and cyanosis upon arm elevation indicate in a patient with a multinodular thyroid?

A

Pemberton’s sign due to multinodular goiter

This sign indicates thoracic inlet obstruction.

33
Q

What does a soft texture of a lymph node indicate?

A

Insignificant

Soft lymph nodes are typically not associated with serious conditions.

34
Q

What texture of a lymph node is consistent with lymphoma?

A

Rubbery

A rubbery consistency can suggest the presence of lymphoma.

35
Q

What does a fixed, firm, hard, and nontender lymph node suggest?

A

Malignancy or granulomatous infection

These characteristics often indicate serious underlying pathology.

36
Q

What does a tender lymph node indicate?

A

Inflammation

Tenderness in lymph nodes is usually associated with inflammatory processes.

37
Q

What is the lifetime risk of thyroid cancer in men?

A

0.6%

This statistic highlights the relatively low risk for men compared to women.

38
Q

What is the lifetime risk of thyroid cancer in women?

A

1.8%

Women have a higher risk of developing thyroid cancer compared to men.

39
Q

What is diffuse enlargement of the thyroid indicative of?

A

Grave’s disease, Hashimoto’s thyroiditis, and endemic goiter

This type of enlargement occurs without the presence of nodules.

40
Q

What could a single nodule in the thyroid indicate?

A

Cyst, benign tumor, or malignancy

Rapid growth, hardness, or lymphadenopathy increases suspicion for malignancy.

41
Q

What often causes multinodular goiter?

A

Iodine deficiency

Multinodular goiter is commonly seen in areas with low iodine intake.

42
Q

What is the consistency of the thyroid in Graves’ disease?

A

Soft, possibly with a bruit

A bruit indicates increased blood flow, commonly associated with hyperthyroid conditions.

43
Q

What is the consistency of the thyroid in Hashimoto’s thyroiditis?

A

Firm

Firmness in the thyroid can suggest autoimmune conditions like Hashimoto’s.

44
Q

What are common symptoms of hyperthyroidism?

A
  • Nervousness
  • Weight loss with increased appetite
  • Sweating
  • Heat intolerance
  • Palpitations
  • Frequent bowel movements
  • Muscle weakness
  • Tremor

These symptoms reflect the increased metabolic activity associated with hyperthyroidism.

45
Q

What are common signs of hyperthyroidism?

A
  • Tachycardia
  • Increased systolic BP
  • Decreased diastolic BP
  • Warm/moist skin
  • Tremor
  • Lid lag
  • Exophthalmos

Signs can help differentiate hyperthyroidism from other conditions.

46
Q

What are common symptoms of hypothyroidism?

A
  • Fatigue
  • Weight gain
  • Dry skin
  • Cold intolerance
  • Edema
  • Constipation
  • Muscle weakness
  • Memory issues
  • Hearing impairment

These symptoms are indicative of decreased metabolic function.

47
Q

What are common signs of hypothyroidism?

A
  • Bradycardia
  • Hypothermia
  • Decreased heart sound intensity
  • Coarse skin
  • Non-pitting edema
  • Hair loss
  • Periorbital edema
  • Peripheral neuropathy
  • Somnolence

These signs reflect the body’s response to low thyroid hormone levels.

48
Q

What does Jugular Venous Distention (JVD) indicate?

A

Heart conditions

Observation for JVD is part of a comprehensive neck exam.

49
Q

What characteristics are typical of benign thyroid nodules?

A
  • Mobile
  • Soft
  • Without associated lymphadenopathy

These features suggest a lower likelihood of malignancy.

50
Q

What characteristics are typical of malignant thyroid nodules?

A
  • Hard
  • Fixed
  • Rapidly growing
  • Associated with cervical lymphadenopathy

These signs raise suspicion for thyroid cancer.

51
Q

What does swelling in posterior auricular and posterior cervical lymph nodes often indicate?

A

Infections or, rarely, malignancies

This type of adenopathy can be a response to localized infections.

52
Q

What does cervical adenopathy indicate?

A

Infections, inflammatory conditions, or malignancies

Enlargement of cervical lymph nodes can have various underlying causes.

53
Q

What is Pemberton’s sign?

A

Facial congestion and cyanosis when the arms are raised

This sign indicates compression of the thoracic inlet by a multinodular goiter.

54
Q

A lymph node that is hard, fixed, and nontender suggests what?

A

Consistent with malignancy or granulomatous infection

This finding is often concerning for serious pathology.

55
Q

What is the most likely diagnosis for a firm, painless nodule on the thyroid in a patient with a family history of thyroid cancer?

A

Thyroid cancer

Family history and radiation exposure are significant risk factors.

56
Q

What is the most likely diagnosis for a patient with diffuse thyroid enlargement and no visible nodules?

A

Diffuse thyroid enlargement, possibly due to Graves’ disease

This condition often presents without nodular formation.

57
Q

What thyroid condition does a soft nodule with a bruit over the lateral lobes most likely indicate?

A

Graves’ disease

The presence of a bruit suggests increased blood flow associated with hyperthyroidism.

58
Q

What is the most likely diagnosis for a patient with nervousness, weight loss, and a rapid heart rate?

A

Hyperthyroidism

These symptoms are classic for an overactive thyroid.

59
Q

What is the most likely diagnosis for a patient with fatigue, weight gain, and bradycardia?

A

Hypothyroidism

These symptoms indicate a deficiency in thyroid hormone.

60
Q

What does prominent neck veins in a seated upright patient suggest?

A

Jugular Venous Distention (JVD)

This can indicate heart failure or other cardiac issues.

61
Q

What does a hard, fixed thyroid nodule with cervical lymphadenopathy suggest?

A

Consistent with thyroid malignancy

These features raise concerns for cancer.

62
Q

What is the most likely diagnosis for a patient with swollen lymph nodes behind the ear and recent upper respiratory symptoms?

A

Posterior auricular and posterior cervical adenopathy due to infection

This presentation is often seen in viral infections.

63
Q

What is the likely diagnosis for a patient with multiple nodules on the thyroid after returning from an iodine-deficient region?

A

Multinodular goiter due to iodine deficiency

Iodine deficiency is a common cause of goiter.

64
Q

What does facial congestion and cyanosis upon arm elevation indicate in a patient with a multinodular thyroid?

A

Pemberton’s sign due to multinodular goiter

This sign indicates thoracic inlet obstruction.