digestive system part 3 Flashcards
what cells control secretion of gastrin in the stomach
G cells
ECF cells function
stimulated by gastrin
stimulate parietal cells to release acid
chief cells function
stimulated by gastrin
release pepsinogen
enteroendocrine cells of intestine (acid)
stimulated by acid
release VIP–> pancreas –> HCO3
release secretin–> liver–> bile
enteroendocrine cells of intestine (digested food)
stimulated by digestive products
release CCK–> gallbladder –> bile
OR release CCK–> pancreas–> enzymes
what is energy balance
energy balance = food intake - energy expenditure
what is the short term regulation of energy
ending individual meals
gherlin, PYY, cholecystokinin (CCK), vagus nerve
long term status of body energy store
leptin
what happens when an obese mouse is with a regular mouse
the obese mouse will get smaller
- obese mouse has no chemical messengers, receives it from the regular mouse and is able to regulate its appetite
what happens when a diabetic mouse is paired with a regular mouse?
the diabetic mouse will stay the same size and regular will starve
- diabetic mouse has no receptors and over produces chemical messenger so regular mouse will stop eating but diabetic mouse has no effect
what happens when diabetic mouse is paired with obese
obese mouse will be able to control its eating
- diabetic mouse is unaffected but obese mouse uses chemical messengers from diabetic (doesn’t starve because it has no chemical messangers of its own)
what is the chemical messenger the obese mouse was unable to produce
leptin
leptin role
suppresses appetite
secreted by white adipose tissue
gherkin
stimulates appetite
secreted by stomach when empty
peptide YY
suppresses appetite
secreted by colon when full