circulatory system part 4 Flashcards
what moderates heart rate
autonomic nerves and adrenal medulla?
equation for mean arterial pressure
MAP = cardiac output x total peripheral resistance
how do arterioles control blood distribution?
vasoconstriction/dilation changes in resistance alter flow
- auto regulation: response of arteriole smooth muscle
- intrinsic factor: metabolic state
- extrinsic factor: nervous/endocrine system
myogenic auto regulation of flow
smooth muscle cells in arterioles are sensitive to stretch
contract (decrease diameter increase resistance) when blood pressure increases
- negative feedback prevents excessive flow of blood
metabolic activity regulates blood flow
levels of metabolites need to match requirements
when low O2 and high waste/CO2 levels - VASODILATION
norepinephrine effects on blood flow
released from sympathetic neurons
causes vasoconstriction
vasopressin (ADH)
released from posterior pituitary
causes vasoconstriction
angiotensin 2
produced in response to decreased blood pressure
causes vasoconstriction
atrial natriuretic peptide (ANP)
produced in response to increased blood pressure
causes vasodilation
what are baroreceptors
stretch-sensitive mechanoreceptors
send nerve signals to medulla oblongata
what is the affect of high baroreceptor firing
vasodilation, decreased force of contraction, decrease heart rate, lower MAP