Digestive System Flashcards
GI components of the pelvic cavity
Large intestine
Anus
GI components of the abdominal cavity
Stomach
Small intestines
GI components of the head and neck
Mouth
Pharynx
Esophagus
6 accessory digestive organs
Teeth Tongue Salivary glands Liver Gall bladder Pancreas
Propulsion
Voluntary and involuntary processes move food through alimentary canal
Peristalsis
Forward movement of food along GI tract
3 steps in peristalsis
Contraction of circular muscles behind bolus
Contraction of longitudinal muscles ahead of bolus
Contraction of circular layer forces bolus forward
Segmentation
Local shimmying on bolus to break it up and mix it with enzymes
Mechanical digestion
Physically prepares food– mixing with saliva and churning in stomach
Chemical digestion
Breaks down food into components with enzymes in the mouth and small intestine
Mechanoreceptors
Sense stretching of stomach wall and triggers churning
Chemoreceptors
Detects acidity, osmolarity and triggers enzyme release
3 reflexes initiated by recpetors
Stimulates secretions
Mixing of luminal content
Movement along alimentary canal
Absorption
Passage from lumen of GI tract into blood. Mostly at small intestine
2 components of the Enteric nervous system
Submucosal nerve plexus
Myenteric nerve plexus
Submucosal nerve plexus
Found in submucosa and controls segmentation. Regulates activity of glands and activates smooth muscle of mucosa
Myenteric nerve plexus
Found between the longitudinal and circular muscle layers of the muscularis externa and controls peristalsis
Mesentery
Double layer of peritoneum holds GI tract down and contains vascular and neural control, stores fat
Lumen
Opening in GI tract (tube)
Mucosa
Innermost lumen layer secretes mucus
Submucosa
Localized muscle layer in lumen, surrounds mucosa
Muscularis Externa
Inner circular layer, outer longitudinal layer, with a myenteric nerve plexus between
Serosa
Outermost lumen layer contributes to the mesentery
Parietal peritoneum
Walls of abdomen and under diaphragm
Visceral Peritoneum
Covers organs
Peritoneal Cavity
Potential space between parietal and visceral layers
Dorsal mesentery
Starts at the back wall and attaches to an organ
Ventral mesentery
Connects two organs, or an organ to the front wall
Retroperitoneal
Organs that stick to the posterior abdominal wall, vascular connection through mesentery
6 retroperitoneal structures
Most of pancreas Kidneys Adrenal glands Duodenum Part of large intestine Aorta and IVC
Lesser Omentum
Ventral mesentery from the lesser curvature of the stomach to the inferior border of the liver
Greater omentum
Dorsal mesentery connects greater curvature of the stomach to the posterior wall. Goes around the small intestine and transverse colon
Falciform ligament
Ventral mesentery attaches superior surface of liver to the anterior abdominal wall
3 branches of abdominal aorta supplying organs
Celiac trunk
Superior mesenteric artery
Inferior mesenteric artery
Gingivae
Gums
Labial frenulum
Connects teeth to gums
Lingual frenulum
Connects tongue to gums
Vestibule
Space between lips and teeth
Tongue
Interlacing bundles of skeletal muscle
Filiform papillae
Surface roughness of tongue manipulates food, smallest and most numerous
Circumvallate papillae
Large 10-12 at back of the tongue, contains taste buds, first sensations of amylase
Sulcus terminalis
Separates tongue into portions where different nerves innervate– 2/3 oral cavity (facial nerve), 1/3 oropharynx (hypoglossal) – covered by lingual tonsil
Intrinsic tongue muscle
Shapes tongue but does not change position
Extrinsic tongue muscle
Alters tongue position (protrusion, retraction, side-to-side)
Adult dental formula
2I, IC, 2PM, 3M x2= 32 teeth
Deciduous dental formula
2I, 1C, 2M
Root of tooth
Anchored to bony components of oral cavity
Dentin
Bulk of the tooth
Pulp cavity
Filled with loos connective tissue, vascular and nervous supply
Cementum
Calcified material for anchoring
Periodontal ligament
Extensions from tooth into bone
Gomphosis joint
Fibrous joint between periodontal ligament and cementum
Saliva
Solvent that digests starch– amylase
How much saliva do we produce a day?
1- 1.5 L
Salivary glands
3 pairs of extrinsic glands innervated by the parasympathetic NS
Buccal glands
Intrinsic salivary glands
Parotid glands
Exocrine gland anterior to ear, between masseter muscle and skin. Opens into vestibule near second upper molar
Which nerve innervates the parotid gland
9
Submandibular gland
Along medial aspect of body of the mandible and opens at base of lingual frenulum
Which nerve innervates the submandibular gland
7
Sublingual gland
Anterior to submandibular gland, opens via 10-12 ducts beneath tongue
Which nerve innervates the sublingual gland
7
Esophagus
Muscular tube, 25 cm in length
Where does the esophagus join the stomach
Cardiac orifice (sphincter near the heart)
Empty esophagus
Mucosa and submucosa are in longitudinal folds
Full esophagus
Folds flatten and trachealis muscle allows expanding
Esophagus musculature
Upper– skeletal muscle
Middle– mixed smooth and skeletal
Lower– smooth muscle
Esophagus blood supply
Cervical region– inferior thyroid artery
Abdominal region– left gastric artery
GERD
Gastro-esophageal reflux disease. Weakening of muscle compromises cardiac sphincters ability to stay permanently contracted
Pyrosis
Heart burn
Dysphagia
Painful eating
Chyme
Gastric secretions and food
Rugae
Longitudinal folds allow stomach to expand
Where does the stomach empty into
Duodenum
Pyloric region
Distal end of stomach
Fundus
Top of stomach
Cardia
Tube in heart for cardiac sphincter
Sphincters
Made by circular layer of muscularis externa
3 layers of the muscularis externa of the stomach
Longitudinal
Circular
Oblique
Oblique layer
Innermost layer contributes to churning
3 vessels supplying stomach
Celiac trunk
Right gastric artery
Gastroduodenal artery
How many unpaired vessels branch off the abdominal aorta?
3
3 branches of the celiac trunk
Left gastric– lesser curvature
Splenic–greater curvature
Hepatic
Right gastric artery
Completes blood supply to lesser curvature
Gastroduodenal artery
Stomach, intestines and greater curvature
Intrinsic factor
Glycoprotein to absorb vitamin B12
Gastric motility
Continually mix food with gastric juice
Small intestine
3m long with 3 regions
Duodenum
Shortest section, C shaped and retroperitoneal. Superior, descending, horizontal and ascending parts
2 ducts in duodenum
Common bile duct
Pancreatic duct
Common bile duct
Bile from liver/gall bladder regulated in duodenum
Pancreatic duct
Pancreatic secretions
2 vessels supplying the duodenum
Celiac trunk
Superior mesentery
Peptic ulcer disease
Erosion of the lining of stomach or small intestine, usually gastric or duodenal
3 causes of ulcers
Heliobacter pylori
Non-steroidal anti-inflammatory drugs (NSAIDS)
Hyper secretion of HCl
Erosion ulcer
Innermost mucosa layer is compromised
Acute ulcer
Perforated up to the oblique layer
Perforating ulcer
Outermost serosa is compromised and stomach contents leak into abdominal cavity
Jejunum
Main site of absorption. Larger lumen with greater vasculature and more folds
Ileum
Terminal portion with thinner walls, fewer folds and less vasculature
Ileocecal valve
Empties ileum contents into cecum
Large intestine
Extends from ileocecal valve to anus. Half the lengt, but greater diameter than small intestine
5 parts of the large intestine
Cecum Ascending colon Transverse Descending Sigmoid
Hepatic flexure
Right sight of large intestine folds over liver
Splenic flexure
Left side of large intestine folds over spleen
Teniae Coli
Three longitudinal ribbons of smooth muscle on the outside of the large intestine. Mesocolic, Free, omental
Haustra
Teniae coli contract length wise to produce bulges in the colon
Omental appendicies
Small pouches of peritoneum filled with fat, along the colon but absent in the rectum
Parts of the large intestine supplied by superior mesenteric artery
Ascending and transverse colon
Parts of the large intestine supplied by inferior mesenteric artery
Descending
Sigmoid
Rectum
Rectum
Last 20 cm, anterior to sacrum and attached to perineum
Anal canal
Opening containing internal and external anal sphincters
Levator Ani
Opens sphincter during defecation
Crohn’s disease
Chronic inflammatory disease leading to mucosal ulceration
Areas effected by Crohns
50% ileum/ascending
30% ileum/jejunum
20% large intestine
Transumbilical plane
Horizontal, through umbilicus– L3/L4 vertebrae
Median plane
Longitudinal through body cutting it into left and right
RUQ (9)
Right lobe of liver Gall bladder Duodenum Head of pancreas Kidney Adrenal gland Hepatic flexure Transverse colon Pyoric region of stomach
LUQ (7)
Liver Body and tail of pancreas Kidney Adrenal gland Splenic flexure Transverse colon Most of stomach
RLQ (7)
Cecum Appendix Ileum Ascending colon Ovary Uterine tube Ureter
LLQ (6)
Sigmoid colon Jejunum Descending colon Ovary Uterine tube Ureter
Bile
Helps break down fat
Liver
Largest internal organ, processes nutrients and secrets bile
4 liver lobes
Right
Left
Quadrate
Caudate– more posterior, above porta hepatis
Falciform ligament
Ventral mesentery separates right and left lobes of liver
Ligamentum teres
Dangly bit of liver attaches to anterior wall
Porta hepatis
(portal triad) Hepatic portal vein, hepatic artery and bile duct
5 functions of the liver
Process nutrients in blood Store glucose and glycogen Store fat soluble vitamins Remove toxic substances Produce bile
Hepatocytes
Liver cells produce bile
Hepatic portal vein
Union of superior mesenteric and splenic veins. Deliver nutrients to liver for processing and storage
Liver lobule
Hepatic portal triads at the periphery and a central vein in the middle
Canniculus
First and smallest branch of bile collecting system. Travels in opposite direction as blood
Sinusioid
Blood filled space between walls of hepatocytes
Kupffer Cells
Immune like cells in between walls of hepatocytes, destroy dead blood cells and detoxify
Hepatic plate
Sinusoid and walls of liver cells that surround them. 1-2 hepatocytes thick, separated by sinusoid
Blood in liver
70% deoxygenated, but nutrient rich blood from portal vein
30% is oxygenated from hepatic artery
Gall bladder
Attached under the right lobe of liver, concentrates and stores bile
Fundus of gall bladder
Big superior bulge, followed by body and neck
Common bile duct
Cystic duct carries stored bile to join with common hepatic duct
Cholecystitis
Inflammation of gall bladder
Gall stones
Crystallization of bile
3 locations of gall stones
Gall bladder
Neck or cystic duct
Common bile duct
Cholecystokinin (CCK)
Stimulated by chyme entering duodenum, releases pancreatic juices and bile, relaxes hepatopancreatic sphincter
Endocrine function of pancreas
Pancreatic islets produce insulin and glucagon
Exocrine function of pancreas
Pancreatic acini make juices
Acinar cells
Secrete 1L of digestive enzymes a day
Secretin
Released in response to HCl, bicarbonate rich pancreatic juice neutralizes acid
What does protein and fat trigger release of
Protein– enzymes
Fat– bile
Gall bladder blood supply
Branches of hepatic artery
Pancreas blood supply
Splenic artery supplies distal end, superior mesenteric supplies head and neck