Digestive system Flashcards
What is the main role of the digestive system?
▫ Break down food
▫ Absorb nutrients
▫ Eliminate indigestible material
* The digestive system is also home to our microbiome
▫ Host bacteria that reside in our large intestine
▫ Huge area of research
▫ Contribute to health and disease states via metabolites
What are the macromolecule nutrients in food?
Proteins, Carbohydrates, Lipids, Nucleic acids.
What are the micronutrients in food?
Vitamins, minerals / trace elements.
What are the 6 processes of the digestive system?
-Ingestion
- Secretion
- Mixing and Propulsion
- Digestion
- Absorption
- Defecation
What is ingestion?
▫ Process of placing food in the mouth
What is secretion?
▫ Release of water, digestive enzymes and acids, salts and buffers into the GI tract
What is mixing and propulsion?
▫ Alternating contraction and relaxation of smooth muscle
▫ Mixes food and secretions
▫ Moves contents down G.I. tract
What is digestion?
▫ Mechanical and Chemical breakdown of food
▫ Breaks down polymers into monomers
▫ Enables passage through epithelium
What are the two types of digestion?
Mechanical and Chemical
What is absorption?
▫ Describes the passage of nutrients and water across the digestive epithelium
▫ Enters either blood or lymph
What is defecation?
▫ Removal of wastes, indigestible material, bacteria, dead cells and other unabsorbed products
How long is the GI tract?
5-7 m long
What are the four layers of the GI tract?
Mucosa, Submucosa, Muscularis and serosa.
What muscle does the muscularis layer contain?
smooth muscle in two orientations - circular and longitudinal.
Does the stomach contain a third muscle layer?
Yes, the inner oblique.
What is the Mucosa?
- Inner most layer, lines GI tract.
- Moist due to glandular secretions.
- Divided into surface epithelium and lamina propria
- Thin smooth muscle layer (muscularis mucosae)
What is submucosa?
- Connective tissue
- Extensive vascularisation, nervous supply and lymphatics.
What is the Muscularis (externa)?
- Muscle layer divided into circular and longitudinal muscle.
- Moves food and fluid through tract by ‘peristalsis’
What is peristalsis?
the involuntary constriction and relaxation of the muscles of the intestine or another canal, creating wave-like movements that push the contents of the canal forward.
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Circular muscles contract behind bolus and relax ahead
* Longitudinal muscles ahead of
bolus contract to shorten the segment
* This sequence pushes bolus through tract
What is the serosa?
- Outermost layer
- Thin connective tissue surrounds tract and extends to form mesentery that anchors tract to abdominal wall.
-Adventitia replaces serosa on oesophagus.
What are the four functions of the stomach?
- Accommodation of ingested food.
- Secretion of gastric juice
- Mixing food, saliva and gastric juice using peristaltic mixing waves to form chyme.
- Secretion of the hormone gastrin.
What are the four sections of the stomach?
Fundus, Cardia, Body, Pylorus
What does the lower oesophageal sphincter do?
Permit entry of food and fluid into stomach.
What does the Pyloric sphincter do?
Controls exit into duodenum