digestive Pt 3 Flashcards
3 subdivisions of SI in order from proximal to distal
- duodenum
- jejunum
- ileum
circular folds
permanent folds; bumps to slow/alter flow of chyme
villi
finger like projections of mucosa
brush border
give a fuzzy appearance
- brush border enzymes complete final carbohydrate + protein digestion
5 types of cells found in the villi/crypts
- enterocytes
- goblet cells
- enteroendocrine
- paneth cels
- stem cells
entercytes
make up the bulk of the epithelium
- in the villi, absorb nutrients and electrolytes
- in the crypts, produce Intestinal juice
goblet cells
secrete mucus in the villi and crypts
enteroendocrine
source of enterogastrones - hormones that inhibit secretions
paneth cells
secretory cells found deep in the crypts - secrete antimicrobial agents
stem cells
continuously divide to produce other cell types - epithelium is renewed every 2-4 days
Peyers patches
aggregate lymphoid nodules, located in the lamina propria
duodenal gland
secrete alkaline mucus to neutralize acidic chyme and prevent duodenal ulcers
Intestinal juice
- 1-2L are secreted daily in response to distension or irritation of the mucosa
- production stimulated by acidic chyme
- slightly alkaline, isotonic with blood plasma
- largely water + mucus from the duodenal glands and goblet cells
why is the slow pace of chyme entering SI crucial
- chyme entering duodenum is hypertonic - to avoid water loss from blood, chyme entry must be slow
- acidic chyme must be neutralized
- takes time for chyme to be mixed with bile and pancreatic juice
ileocecal valve
typically closed; relaxes to admit chyme into the LI; closes to prevent regurgitation