Digestive Pt 2 Flashcards
Be prepared to label the different regions and anatomical features of the stomach
what is the term for a bolus of food after it is undergoing digestion in the stomach
chyme: liquified slurry of food
modified tunics
- muscularis has an added internal, oblique layer to allow increased mixing and churning
secretory cells
- mucus neck cells
- parietal cells
- chief cells
- enteroendocrine cells
mucus neck cells
produce thin, soluble mucus
parietal cells
produce HCI and secrete intrinsic factor (required to absorb B12)
chief cells
secrete pepsinogen and lipases
enteroendocrine cells
secrete chemical messengers into the lamina propria as well as gastrin
mucosal barrier
produced to protect the stomach
- thick coating of bicarbonate-rich mucus
- tight junction between epithelial cells
- quickly replacement of damaged mucosal cells by stem cells
peptic/gastric ulcers
erosion of the stomach wall - cause gnawing, epigastric pain
- pain appears 1-3 hrs after eating and resolves with eating again
- ulcers are linked to peritonitis and H. pylori
propulsion
peristalsis
mechanical breakdown
churning
digestion
breakdown of proteins by HCI and pepsin (rennin in infants)
absorption
only lipid-soluble substances - alcohol and aspirin
secretion of intrinsic factor
essential for B12 absorption and maturation of RBCs
which branch of the autonomic nervous system increases gastric secretions
- stimulation by vagus nerve
- sympathetic Nervous system decreases secretion
gastrin
- stimulate secretion of HCI by the stomach
3 phases of the gastric secretions
- cephalic/reflex phase
- gastric phase
- Intestinal phase
cephalic/reflex phase
triggered by smell, taste, and sight; act via the vagus nerve
gastric phase
triggered by stretch receptors and/or chemical stimuli - partially digested protein, caffeine, rising pH
- activates G cells to secrete gastrin
- gastrin initiates release of HCI
- low pH or firing of the SNS will inhibit gastrin
Intestinal phase
partially digested food enters the SI and triggers the release of intestinal gastrin
- distention of the SI and/or presence of acidic, fatty, or hypertonic chyme will inhibit gastric secretions - protects the SI from excess acidity and being overwhelmed
enterogastric reflex
short reflexes by the enteric nervous system and long reflexes by the sympathetic and vagus nerves inhibit acid secretion