Digestion: Protein (M2) Flashcards

1
Q

essential amino acids

A

histidine
isoleucine
leucine
lysine
methionine
phenylalanine
threonine
tryptophan
valine

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2
Q

what are amino acids

A

building blocks of proteins

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3
Q

what do amino acids form and how

A

join together in peptide bond to form peptides and polypeptides

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4
Q

what are the 3d shapes peptides and polypeptides can take on through various bonds

A

hydrogen bonds
ionic bonds
van der waals interactions
hydrophobic interactions
disulfide bridges

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5
Q

where does protein digestion begin

A

stomach

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6
Q

what is gastric juice

A

ph 1.3 - 3.5
stomach acid denatures proteins.
pepsin hydrolyzes peptide bonds

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7
Q

what do stomach parietal cells produce

A

carbonic acid (H2CO3) from water (H20) and carbon dioxide (CO2)

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8
Q

what does carbonic acid spontaneously dissociate into

A

hydrogen ion (H+) and bicarbonate ion (HCO3^-)

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9
Q

what does an anion exchanger protein do

A

transports bicarbonate ion (HCO3^-) out of the cell and chloride ion (Cl-) into the cell

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10
Q

what forms hydrochloric acid (HCl)

A

hydrogen ion (H+) bonds with chloride ion (Cl-)

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11
Q

what does HCl do

A

denatures salivary amylase.
denatures proteins.
activates pepsinogen to pepsin

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12
Q

where does protein digestion continue after the stomach

A

lumen of the small intestine

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13
Q

what is secreted from the pancreas and what is it secreted into

A

bicarbonate (HCO3^-), trypsin, chymotrypsin, and carboxypeptidase.
secreted into small intestine

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14
Q

what is bicarbonate

A

buffer that neutralizes acidic stomach contents

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15
Q

what hydrolyzes peptide bonds

A

trypsin, chymotrypsin, carboxypeptidase

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16
Q

where are peptidases secreted from

A

the small intestine.
hydrolyze peptides into amino acids

17
Q

what are amino acids absorbed into

A

enterocytes of the intestinal mucosa to reach blood capillaries

18
Q

can substances pass between epithelial cells

A

no, because these cells are bound by tight junctions

19
Q

once in the blood capillaries, where are amino acids transported to and how

A

to the liver via hepatic portal vein

20
Q

what are amino acids used for in the liver

A

protein synthesis.
converted into glucose.
converted into fatty acids.
transported to peripheral tissues for protein synthesis.

21
Q

how much protein is eliminated by the colon

A

small amount of protein