Digestion of Carbohydrates and Proteins Flashcards

1
Q

What are the principle dietary nutrients?

A
  • Carbohydrate
  • Protein
  • Fat
  • Vitamins
  • Minerals
  • Water
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2
Q

What are the 3 monosaccharides?

A
  • Glucose
  • Galactose
  • Fructose
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3
Q

What are hexose sugars?

A

Breakdown products of complex CHOs which are absorbed by small intestine

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4
Q

What are disaccharides?

A

2 monosaccharide linked together by glycosidic bond

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5
Q

How are disaccharides broken down?

A

Broken down to constituent monomers by brush border enzymes in small intestine

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6
Q

What is lactose composed of?

A

Glucose and galactose

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7
Q

What is sucrose composed of?

A

Glucose and fructose

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8
Q

What is maltose composed of?

A

Glucose and glucose

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9
Q

What enzyme breaks down lactose?

A

Lactase

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10
Q

What enzyme breaks down sucrose?

A

Sucrase

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11
Q

What enzyme breaks down maltose?

A

Maltase

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12
Q

Name 3 polysaccharides.

A
  • Starch
  • Cellulose
  • Glycogen
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13
Q

What is starch?

A

Plant storage form of glucose

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14
Q

What is cellulose?

A

Constituent of plant cell walls

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15
Q

What is glycogen?

A

Animal storage form of glucose

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16
Q

What is the structure of a-amylase?

A

Glucose linked in straight chains

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17
Q

What is the structure of amylopectin?

A

Glucose chains highly branched

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18
Q

What is the structure of starch?

A

Glucose monomers linked by a-1,4 glycosidic bonds

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19
Q

What breaks down starch?

A

Amylases

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20
Q

Where are amylases found?

A
  • Saliva

- Pancreas

21
Q

What is the structure of cellulose?

A

Unbranched, linear chaind of glucose monomers linked by B-1,4 glycosidic bonds

22
Q

Why is cellulose known as dietary fibre?

A

There is no enzymatic digestion in vertebrates

23
Q

What is the structure of glycogen?

A

Glucose monomers linked by a-1,4 glycosidic bonds

24
Q

Where are the disaccharide ‘ases’ expressed?

A

Brush border

25
Where is the apical membrane found?
Microvilli
26
Where is the basolateral membrane found?
Membrane furthest from the lumen
27
How are the cells in the small intestine joined?
Tight junctions
28
How can molecules pass form the gut tube into the body?
- Transcellular - Paracellular - Vectorial transport
29
What is the name of the transporter that transports glucose into the cell?
SGLT1
30
What is the name of the transporter that transports glucose out of the cell?
GLUT-2
31
Other than glucose what does SGLT1 also recognise?
Galactose
32
What is the name of the transporter that transports fructose into the cell?
GLUT-5
33
What is the name of the transporter that transports fructose out of the cell?
GLUT-2
34
What are proteins?
Polymers of amino acids linked together by peptide bonds
35
How do proteins differ?
Amino acids used and chain length
36
What do proteins often undergo?
Post-translational modification
37
What are small proteins with chains 3-10 amino acids long known as?
Peptides
38
What are proteases/peptidases?
They are enzymes which hydrolyse peptide bonds and reduce proteins or peptides to amino acids
39
What does endopeptidase do?
They act on the internal part of a protein to produce 2 smaller peptides
40
What does exopeptidase do?
They act on the terminal amino acid of a protein to remove 1 amino acid at a time
41
Where do aminopeptidases act?
At the amine end of a protein
42
Where do carboxypeptidases act?
At the carboxylic end of a protein
43
What is the generic amino acid transporter?
SAAT1
44
What enters the cell along with amino acids?
Sodium
45
What is the name of the transporter that transports dipeptides?
PepT1
46
What is transported along side dipeptides?
Hydrogen
47
What is the name of the transporter that removes hydrogen from the cell?
NHE3
48
What enters the cell using the NHE3 transporter?
Sodium
49
What happens to dipeptides once they are in the cell?
They can pass through into the blood