Digestion and Absorption of Carbohydrates and Proteins Flashcards

1
Q

What is the name for the two enzymes secreted in the mouth?

A

Lingual Lipase

Amylase

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2
Q

For secretion of saliva, which cells do this?

A

Acini cells

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3
Q

For secretion of saliva, which cells help excrusion of the contents of the acini cells?

A

Myoepithelial (basket) cells

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4
Q

State the five cell types located within the stomach

A
Mucuous cells
Parietal / oxytic cells
Chief cells
Enteroendocrine cells
Stem cells
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5
Q

What is the function of Mucous cells?

A

Secretion of mucus to protect the epithelium from acid secretions

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6
Q

What is the function of Parietal / Oxyntic cells?

A

Secretion of HCl and intrinsic factor for B12 absorption

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7
Q

What is the function of Chief cells?

A

Secretion of pepsinogen (pepsin precursor)

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8
Q

What is the function of Enteroendocrine cells?

A

Secretion of protein hormones i.e.VIP and somatosatin

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9
Q

What is the function of the stem cells?

A

Give rise to new cells to replace old mucosal / epithelial cells

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10
Q

What do G cells in the pyloric antrum secrete?

A

Gastrin

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11
Q

What are the phases of Gastric secretion called?

A

Cephalic phase
Gastric phase
Intestinal phase

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12
Q

What regulates the cephalic phase of gastric secretion?

A

Sight / Smell / Taste cues via the vagus nerve

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13
Q

What three things stimulate the Parietal / Oxyntic cells to secrete acid?

A

Histamine
Gastrin
Acetylcholine

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14
Q

Somatostatin is released by which cells?

A

D cells

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15
Q

D cells secrete what?

A

Somatostatin

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16
Q

What does GIP mean? What is it now known as and what is its role?

A

Gastric Inhibitory Polypeptide

Known as Glucose-dependent insulinotropic polypeptide. Stimulates insulin secretion in response to glucose in the duodenum

17
Q

Proton pump inhbitors inhibition which type of cell in stomach?

A

Parietal / Oxyntic cells

18
Q

How long is the small intestine?

A

20 feet long

19
Q

Describe what the small intestine mucosa is like

A

Microvilli, with absorptive enterocytes and mucus secreting goblet cells

20
Q

For the microvilli of the small intestine, where does the venous drainage lead to..?

A

Hepatic portal vein

21
Q

For the microvilli of the small intestine, explain the function of the lacteal

A

The lacteal drains into the lymphatic system which enters circulation into the thoracic duct

22
Q

Where are the stem cells of the microvilli of the small intestine located?

A

At the base of the crypt

23
Q

What is the life span of the small intestinal mucosa?

A

2-3 days

24
Q

What does salivary amylase digest?

A

Starch

25
Q

What are the three components of the small intestine?

A

Duodenum
Jejunum
Ileum

26
Q

State the name of 3 protease enzymes

A

Trypsin
Chymotrypsin
Elastase

27
Q

Pepsinogen gives rise to…?

A

Pepsin

28
Q

What is the precursor of chymotrypsin?

A

Chymotrypsinogen

29
Q

Elastase’s zymogen precusor is..?

A

Pro-elastase

30
Q

What is the function of Maltase?

A

Maltose —- 2 x Glucose

31
Q

What is the function of Lactase?

A

Lactose —- Glucose + Galactose

32
Q

What is the function of Sucrase?

A

Sucrose —- Fructose + Glucose

33
Q

What can be transported by the Na+ / Glucose symporter?

A

Glucose and Galactose

34
Q

What is the UK recommended intake for dietary fibre?

A

11-12g per day

35
Q

Define glycaemic index

A

The ability of carbohydrate food to increase blood glucose levels

36
Q

What is considered a “low” glycaemic index?

A

< 55