Digestion and Absorption of Carbohydrates and Proteins Flashcards
What is the name for the two enzymes secreted in the mouth?
Lingual Lipase
Amylase
For secretion of saliva, which cells do this?
Acini cells
For secretion of saliva, which cells help excrusion of the contents of the acini cells?
Myoepithelial (basket) cells
State the five cell types located within the stomach
Mucuous cells Parietal / oxytic cells Chief cells Enteroendocrine cells Stem cells
What is the function of Mucous cells?
Secretion of mucus to protect the epithelium from acid secretions
What is the function of Parietal / Oxyntic cells?
Secretion of HCl and intrinsic factor for B12 absorption
What is the function of Chief cells?
Secretion of pepsinogen (pepsin precursor)
What is the function of Enteroendocrine cells?
Secretion of protein hormones i.e.VIP and somatosatin
What is the function of the stem cells?
Give rise to new cells to replace old mucosal / epithelial cells
What do G cells in the pyloric antrum secrete?
Gastrin
What are the phases of Gastric secretion called?
Cephalic phase
Gastric phase
Intestinal phase
What regulates the cephalic phase of gastric secretion?
Sight / Smell / Taste cues via the vagus nerve
What three things stimulate the Parietal / Oxyntic cells to secrete acid?
Histamine
Gastrin
Acetylcholine
Somatostatin is released by which cells?
D cells
D cells secrete what?
Somatostatin
What does GIP mean? What is it now known as and what is its role?
Gastric Inhibitory Polypeptide
Known as Glucose-dependent insulinotropic polypeptide. Stimulates insulin secretion in response to glucose in the duodenum
Proton pump inhbitors inhibition which type of cell in stomach?
Parietal / Oxyntic cells
How long is the small intestine?
20 feet long
Describe what the small intestine mucosa is like
Microvilli, with absorptive enterocytes and mucus secreting goblet cells
For the microvilli of the small intestine, where does the venous drainage lead to..?
Hepatic portal vein
For the microvilli of the small intestine, explain the function of the lacteal
The lacteal drains into the lymphatic system which enters circulation into the thoracic duct
Where are the stem cells of the microvilli of the small intestine located?
At the base of the crypt
What is the life span of the small intestinal mucosa?
2-3 days
What does salivary amylase digest?
Starch
What are the three components of the small intestine?
Duodenum
Jejunum
Ileum
State the name of 3 protease enzymes
Trypsin
Chymotrypsin
Elastase
Pepsinogen gives rise to…?
Pepsin
What is the precursor of chymotrypsin?
Chymotrypsinogen
Elastase’s zymogen precusor is..?
Pro-elastase
What is the function of Maltase?
Maltose —- 2 x Glucose
What is the function of Lactase?
Lactose —- Glucose + Galactose
What is the function of Sucrase?
Sucrose —- Fructose + Glucose
What can be transported by the Na+ / Glucose symporter?
Glucose and Galactose
What is the UK recommended intake for dietary fibre?
11-12g per day
Define glycaemic index
The ability of carbohydrate food to increase blood glucose levels
What is considered a “low” glycaemic index?
< 55