Digestion and Absorption (Lecture four) Flashcards
Define digestion:
Breaking down of food into small units that can be absorbed.
Define Absorption:
Transport of nutrients from the intestine to the blood or lymph systems.
What is the first part of the GI tract involved in digestion?
The Mouth
How is the mouth involved in digestion?
Chewing mechanically breaks up food, increasing its surface area. Saliva aids in digestion.
After the mouth what is the next part of the GI tract?
The esophagus. (simply transports food)
After the esophagus is the? and what is its function?
The stomach.
1.5L j shaped bag that stores food.
Very little absorption occurs here besides water and alcohol.
Food mixes with gastric gases which further breaks it down.
Regulates the digestion of food.
Describe the small intestine and its specialized structures:
Duodenum, Jejenum, Ilium.
Plicae, (folds that increase SA) and villi + microvilli for increased absorption into the underlying capillary network
Each villus has a lacteal too (lymph)
Whats the function of the gall bladder?
Stores, concentrates and releases bile.
Bile facilitates the absorption of fats (emulsification)
Released through the hepatic duct which feeds into the duodenum
What is the function of the pancreas?
Endocrine and exocrine organ. Releases digestive juices into the duodenum
Function of the large intestine?
Absorbs water and electroclytes.
Stores waste before excretion.
What is the transit time of food in the GI tract before excretion?
1-3 days typically.
Time food spends in the digestive system.
What is motility?
The movement of food within the digestive system.
How is motility achieved?
Peristalsis - mixes and moves food.
When is peristalsis increased?
post meals.
How long does digestion take?
4-6hrs
BUT is dependent on the nutrient
How is CHO digestion started?
Digestion starts in the mouth.
800-1500mL Saliva released per day
99.%% water but contains a-Amylase which breaks down CHO
CHewing increases surface area for contact with amylase
How does CHO digestion occur in the stomach?.
Acid slows amylase action.
CHO mostly oligosaccharides
passes through to duodenum
How does the small intestine promote CHO digestion?
pH (higher than stomach) increase activating enzymes for digestion.
Small glucose polymers (dextrose) and maltose mostly present.
Unique enzymes present at the villus and microvilli
What are the enzymes present at the villi and microvilli/
Maltase - Maltose to 2 x Glucose
Sucrase - Sucrose to glucose and fructose
Lactase - Lactose to glucose and galactose
Is fibre digested?
If fibre is composed of cellulose then NO
How does lipid digestion start?
Silivia contains (lingual) lipase.
- Splits glycerol into three FA
- Gastric lipases continue TG breakdown
- Lipases account for 10-30% TG digestion.
How does lipid digestion occur in the small intestine?
Bile and pancreatic lipases are secreated.
Bile aids in emulsification - (the lipases break mono,di, TG into FA) so the FA forms small droplets, allowing them to remain in water.