Digestion and Absorption extra Flashcards
what are the functions of stomach?
- Storage of food
- Churn and mix food with gastric secretions–>Digestion
- Acid and pepsin secretion
- Slow emptying of digestive contents into small intestine
Stomach secretes alkali, what does that help to do?
- Protect against acid damage
* Ulcers caused by Helicobacter pylori
Stomach secretes acid (HCl), what does that help to do?
- breakdown of connective tissue, muscle fibres
- activates pepsin
- solubilises calcium and iron
- acts as barrier to microbes
Stomach secrets intrinsic factor, what does that help to do?
• Essential for the absorption of vitamin B12
What are the types of cell in the small intestine mucosa and what are their functions?
- Absorptive cells: digestive enzymes, absorption
- Goblet cells: produce mucous
- Granular cells (cells of Paneth): enzymes
- Endocrine cells – hormone production
Where does the bulk if lipid emulsification takes place?
duodenum of small intestine
What are the exocrine functions of the small intestine
pancreatic juice (enzymes)- helps break down fats, carbohydrates and proteins and alkali secretions.
What are the endocrine functions of the small intestine
secretion of insulin and glucagon.
What are the functions of the liver
- Production and secretion of bile acid and alkaline fluid
- Degradation and conjugation of waste metabolic products
- Detoxification
- Regulation of nutrient metabolism
where is bile secreted,synthesised and stored in and released into.
- Secreted in the liver
- synthesised in hepatocytes (liver cells)
- stored in gallbladder
- released into the duodenum after a meal
What are the functions of bile acid
- emulsification of fat particles
- help in absorption of fats by forming complexes called micelles
What happens to the carbohydrate and protein not digested in the small intestine
It is fermented by the colonic microflora/ gut flora to short chain fatty acids and gases such as:
• Acetic, propionic and butyric acid (short chain fatty acids).
They all have some health benefits and act as an energy source.
Where is the enzyme required for lactose digestion found?
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