DIGESTION AND ABSORPTION Flashcards
digestion
digestion can be defined as a biological process in which large biological molecules are hydrolysed into smaller biological molecules to be absorbed across the cell membrane.
digestion of carbohydrates needs
- Amylases
- Membrane bound disaccharidases
digestion of carbohydrates
- amylase is produced by pancrease and salivary gland. amylase hydrolyses the polysaccharides into disaccharide maltose by hydrolysing the glycosidic bonds.
- once the digestion of carbohydrates occurs in the mouth, it passes down to the stomach through oesosphagus. the hydrochloric acid in the stomach inactivates the amylase.
- the next step of digestion occurs in the duodenum. pancreatic amylase is secreted by pancrease which continues the breakdown of starch and glycogen to disaccharides which are then broken down into monosaccharides by enzymes lactase, maltase and sucrase. these are then absorbed across the intestinal epithelium into the blood stream to be transported to different cells in the body.
SUCRASE AND LACTASE are the membrane bound enzymes which hydrolyses the disaccharide sucrose and lactose into monosaccharides.
peristalsis
the rhythmic contraction of the circulatory muscles in the gut is known as peristalsis.
digestion in mouth ( mastication )
- food is chewed by the teeth which increases the surface area . salivary glands produce saliva. salivary amylase is secreted and catalyses the breakdown of carbohydrates ( starch) into some disaccharides.
swallowing
the tongue presses against roof of the mouth . the soft palate closes the nasal cavity and the epiglottis closes the trachea.
enzymes in protein digestion
- endopeptidases
- exopeptidases
- membrane bound dipeptidases
digestion of protein
- protein digestion begins in the lumen of the stomach. protein are large molecules that are broken down by the enzymes; endpeptidases, exopeptidases and membrane bound dipeptidases.
- endopeptidases hydrolyses the peptide bonds between amino acids in middle of the polymer chain and exopeptidases hydrolyses peptide bond in the end of the polymer chain. dipeptides are produced as aresult which are then hydrolysed by membrane bound dipeptidases enzymes to amino acids which is then released in cytoplasm.
enzymes in carbohydrate digestion
- salivary amylase and membrane bound disaccharidases
substances required in lipid digestion
lipase and bile salts
digestion of lipids
it occurs in two stages : physical digestion ( emulsification ) and chemical digestion ( lipase)
physical digestion ( emulsification)
bile salts are produced in liver. lipids are coated into bile salts to create an emulsion. emulsification is a process where lipids are broken down into tiny droplets (micelles) these tiny droplets increases the s.a enabling a faster hydrolysis rxn for lipase.
inc s. a —- more enzymes can be attatcged — more enzyme substrate complex — faster rxn
chemical digestion ( lipase )
lipase is an enzyme produced in pancrease which hydrolyses the ester bonds between tiglycerides to form monoglycerides and fatty acids.
micelles ( tiny droplets)
micelles are water soluble vesicles made up of monoglycerides, fatty acids, glycerol and bile salts.
micelles deliver the fatty acids, monoglycerides and glycerol in the epithelial cells of ileum for absorption.
where does absorptio occur
epithelium cells lining the ileum