Dietary Supplements for Men/Cancer prevention Flashcards

1
Q

T/F: There is no specific normal or abnormal PSA but trends matter most

A

True

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2
Q

What are the dietary supplements that men take for BPH

A

Saw palmetto, Prunus africana, Stingin nettles

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3
Q

Which native american berry is used for BPH

A

Saw palmetto

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4
Q

What are the two MOAs of saw palmetto

A

Inhbitis lipoxygenase and cyclooxygenase reducing edema and inflammation, Inhibits 5-alpha-reductase causing less conversion of testosterone to dihydrotestosterone

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5
Q

T/F: Saw palmetto reduces the size of the prostate

A

False: Saw palmetto does not reduce the size of the prostate

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6
Q

T/F: Saw palmetto use should be evaluated on serum PSA reduction

A

False: Saw palmetto use should be evaluated by symptomatic improvement

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7
Q

What are possible cautions of saw palmetto

A

Increased bleeding time, increased LFTs and bilirubin

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8
Q

What can increase the bioavailability of saw palmetto

A

softgel capsule and eating with a fatty meal

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9
Q

What is the dose for saw palmetto

A

320 mg daily

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10
Q

What is the african herabal remedy for BPH

A

Pygeum africana

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11
Q

What are the 3 MOA of pygeum

A

Inhibits binding of androgen to androgen receptor, inhibitis 5-alpha-reductase (less dihydrotestosterone), inhibits 5-lipoxygenase meabolite production

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12
Q

What is the most used dose for pygeum, when should symptoms improve

A

75 to 100 mg per day, up to 3 months

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13
Q

When using stingin nettles for the prostate what part of the plant has the best efficacy

A

Dried roots (Leafs is for allergies)

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14
Q

What are the three MOA of stinging nettles

A

Inhibits the binding of sex hormone binding globulin to prostate cells, inhibits 5-alpha-reductase, inhibits growth factor activity

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15
Q

What are improvements sen after stinging nettles use

A

Increase urine volume, reduced serum levels of SHBG, reduced postvoid volume

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16
Q

What is the defintion of chemoprevention

A

The use of natural an/or synthetic agents to prevent, slow or reverse the process of carcinogenesis

17
Q

T/F: Mixture of green teat is good for chemoprevention

A

true

18
Q

What is the most concerning fact about green tea

A

Probably hepatoicity

19
Q

T/F:Black pepper extract has a drug drug interaction with curucmin

A

True

20
Q

What are levels that indicate excess, normal, and deficient vitamin D status, intoxication

A

Greater than 55 ng/ml, 25 to 55 ng/ml, less than 10 ng/ml, greater than 150 ng/ml

21
Q

What is the goal for vitamin D in deficient people, how should people be dosed

A

greater than 30 ng/ml, 1000 IU/day

22
Q

T/F: 100 international units of vitamin D raises internal vitamin D by 1 ng/ml

A

True