dialysis and transplantation Flashcards

1
Q

when is renal replacement therapy indicated

A

eGFR < 10ml/min or biochemical abnormalities

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2
Q

types of renal replacement therapy

A

transplant
haemodialysis
peritoneal dialysis
conservative kidney managemnt

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3
Q

types of haemodialysis

A

satellite/hospital and home

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4
Q

types of peritoneal dialysis

A

continuous ambulatory peritoneal dialysis CAPD and automated peritoneal dialysis APD

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5
Q

restrictions for dialysis

A

fluid - urine output, interdialytic weight gain
diet- potassium, sodium, phosphate

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6
Q

fluid balance in dialysis patients

A

usually restricted to 500-800ml/24hrs intake in haemodialysis patients

usually more liberal intake as continuous ultrafiltration is often achieved in peritoneal

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7
Q

peritoneal dialysis where

A

instilled into peritoneal cavity via a tunnelled cuffed catheter using the peritoneal mesothelium as a dialysis membrane

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8
Q

drugs needed when on dialysis

A

erythropoietin injections
IV iron
vitD
phosphate binders with meals
heparin
water soluble vitamins
antihypertensives soemtimes

for PD antibiotics if peritonitis risk

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9
Q

transplant complications

A

bleeding, thrombosis, lymphocele, infections

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10
Q

types of donors

A

DNC- brain dead
DCD- cardiac dead
living related
spouse
altruistic

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11
Q

living donors or dead donors better

A

living. survival better

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12
Q

immunosuppressive agents used to prevent what

A

T cell mediated and antibody mediated rejection

basiliximab
tacrolimus
corticosteroids
cyclosporin
mycophenolate mofetil

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13
Q

post transplant risks

A

diabetes
infection eg UTI, CMV, BK virus
cancer- skin, lymphoma, renal, melanoma, leukemia

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14
Q

how long do you have after death to retrieve kidney

A

120 mins, 2 hours

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15
Q

how long wait asystole before surgery

A

5 mins

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16
Q

what must you do before retrieving organ

A

tell family
authorisation
offering of organs to transplant centres
confirm death

17
Q

haemodialysis access points

A

AV fistula
AV prosthetic graft
temp tunnelled or temp venous catheter

18
Q

who decides what dialysis used

A

patient. education and shared decision

19
Q

who decides what dialysis used

A

patient. education and shared decision

20
Q

investigations before transplant

A

Virology status: CMV, HCV, HBV, HIV, VZV, EBV
Tuberculosis testing
no active infections
no cancer
no severe comorbidity