Diagnostic radiology - Interventional radiology Flashcards

1
Q

Indication for intervention radiology in vascular diseases?

A
  • Aortic aneurysms
  • Pulmonary embolism
  • Vascular access
  • Varicose veins
  • Vascular malformations
  • Peripheral artery disease
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2
Q

3 procedures for oncology treatment or assessment by IR?

A
  • Guided biopsy
  • Percutaneous Ablation: Curative treatment for small tumors
  • Endovascular embolization: Palliative/ curative treatment for multiple tumours
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3
Q

5 procedures for GI tract disease treatment by IR

A
Abscess drainage 
Treat complications of transplant 
Biliary stenting and biliary drainage 
Liver cancer 
Nutritional support/ Gastrostomies
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4
Q

5 neurovascular conditions treated by IR

A
Acute ischemic stroke 
Venous thrombosis
Aneurysms 
AVM 
Arteriovenous fistulae
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5
Q

5 genitourinary conditions treated by IR

A
Stones 
BPH 
Fibroids 
Nephrostomies 
Renal cancer
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6
Q

4 procedures for MSS treatment by IR

A

Vertebroplasty/ kyphoplasty

Spinal injections

Joint injections

Biopsies and tumor ablation

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7
Q

3 advantages of IR over conventional surgery

A

 More precise = safer (avoid
hitting/injuring major vessels, organs)

 Most done under local anaesthesia = suitable for patients who may not be surgical candidates

 Reduced hospital stay (some can be done
as day case), faster recovery

 Provide additional diagnostic information

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8
Q

3 limitations of IR

A
  • Ionizing radiation (some)
  • Not universally applicable (e.g. huge lesions)
  • Emerging techniques with less clinical evidence
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9
Q

Function of Image guided biopsy?

Examples?

A

Obtain sample to help Dx: Microscopy, biochemistry, Histology or Cytology tests

Fluid or solid aspiration or drainage

  • Fine Needle Aspiration for cytology
  • Core biopsy for histology
  • Trephine biopsy for bone marrow
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10
Q

2 modalities of image guidance for biopsy?

give examples of procedures

A
  • US (e.g. endobiliary forceps biopsy, transrectal prostate biopsy)
  • CT (e.g. adrenal venous sampling, transjugular liver biopsy)
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11
Q

Advantage of CT guided biopsy over US?

A
  • Visualize structures without obstruction, wider field of view (US cannot penetrate bone, overlying fat, fluid …etc)

-

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12
Q

Indication for CT-guided biopsy?

A

 Thorax

 Abdomen: pancreas, adrenal gland, bowel, retroperitoneal masses (clearer visualization than US due to overlying bowel and fat)

 Neck masses not seen on US

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13
Q

Complications for CT guided biopsy

A

1) Vascular damage:
- Bleed (e.g. pararenal hematoma)
- Arteriovenous fistulas (e.g. post renal biopsy)
- Pseudoaneurysm

2) Infection

3) Organ injury:
e. g. Puncture normal pancreas = pancreatitis
e. g. Lung biopsy: Pneumothorax, Haemoptysis

4) Needle tract tumour seeding (rare)

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14
Q

4 modalities of image guidance for percutaneous drainage?

A

fluoroscopy, ultrasound, CT and MRI

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15
Q

Which approach is best for Image guided pelvic abscess drainage?

A
  • Posterior approach through gluteal muscle

- Insert catheter for continuous abscess drainage

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16
Q

Complications of image guided drainage of liver (or other) abscess?

A

 Sepsis (pus release to blood/ surrounding)

 Hemorrhage (needle hits blood vessel)

 Death (secondary to sepsis or hemorrhage)

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17
Q

Hydatid cysts:

  • CT findings?
  • IR treatment?
A

CT findings:
 Well-defined, hypoattenuating, with distinguishable wall
 Wall calcification (50%)
 Daughter cysts (75%)

Percutaneous drainage:
 Pretreatment with metronidazole
 Instill sclerosing agent

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18
Q

Outline a simplified procedure of Percutaneous transhepatic biliary drainage

A
  1. Needle punctures bile duct through the skin and liver
    (e. g. with dilated ducts)
  2. Inject contrast material to opacify the bile ducts using fluoroscopy
  3. Pass a guide wire through the needle into the bile ducts and maneuver into the duodenum
  4. Pass a drainage catheter (with side holes) over the guide wire into the duodenum through the obstruction
  5. Withdraw the guide wire
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19
Q

Indications for Percutaneous transhepatic biliary drainage

A

relieves / drains biliary obstruction:

  • obstructive jaundice/ malignancy biliary obstruction- use stenting
  • biliary sepsis
  • Post-operative bile leaks
  • Before surgery to decompress the biliary system
  • During ablation to protect biliary tree
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20
Q

2 main types of Percutaneous drainage

1 precautionary procedure for both

A

Percutaneous transhepatic biliary drainage
Percutaneous nephrostomy

Antibiotic coverage for both

21
Q

4 acute complications of Percutaneous transhepatic biliary drainage

A

 Bleeding into biliary system/ post-PTBD bleed (most
common) = hypotensive

 Infection – septic shock

 Pancreatitis (rare)

 Puncture of other organs – lung, kidney

22
Q

Delayed complications of Percutaneous transhepatic biliary drainage

A

 Biliary sepsis (cholangitis) – bacteria attach to foreign body

 Catheter migration – dislodges when patient moves around

 Bile leak into peritoneal cavity

 Metastatic seeding

 Skin infection

23
Q

Image guidance modality for percutaneous nephrostomy

24
Q

Outline simplified procedure of percutaneous nephrostomy

A
  1. Puncture the calyx through the skin
  2. Inject contrast material to opacify the collecting
    system using fluoroscopy
  3. Pass a guide wire through the needle into the ureter
  4. Pass the drainage catheter over the wire and place into the ureter/ renal pelvis
25
Indications for percutaneous nephrostomy
- Kidney obstruction (benign or malignant) and hydronephrosis - Urinary leakage secondary to trauma/ infection/ neoplasm - Before instrumentation for stone extraction, stricture dilation - Create a tract for stone extraction during lithotripsy ***Must use antibiotic coverage***
26
Complications of percutaneous nephrostomy
 Haemorrhage (pseudoaneurysm, post-PCNL bleeding, hypotensive, tachycardic, shock) / sepsis  Pain, catheter malfunction  Puncture: Pneumothorax, peritonitis, urinoma (urine leaks into the hole created) (rare)  Death: 0.2%
27
4 types of image-guided vascular access
- Peripherally inserted central catheter (PICC) at brachial and basilic veins - Temporary central line (IJV) - Tunneled catheter (Hickman) - Implanted subcutaneous port
28
Function of image guided angiography and embolization? Give one example.
Transcatheter embolization of bleeding sites > stop acutely bleeding viscera E.g. percutaneous coil embolization of the left testicular vein for varices e.g. Gastroduodenal artery embolization from duodenal ulcer
29
Image- guided Treatment for carotid blowout after radiotherapy for NPC?
Stenting and embolization of lacerated vessels leaking pseudoaneurysm at cervical ICA >> use pipeline stent to seal off the leakage >> no more carotid blowout (lower risk of rupturing)
30
Image- guided Treatment for intracranial aneurysms to reduce risk of rupture?
endovascular coiling for intracranial aneurysm
31
Image- guided Treatment for transient ischemic attack from carotid artery plaque ?
Angioplasty & stenting
32
Image- guided Treatment for renal artery stenosis
PTAS (percutaneous transluminal angioplasty with stent)
33
Image-guided percutaneous treatment for tumors? Which modality of imaging for guidance? Mechanism?
Percutaneous ablation of cancer US/CT/MRI/ Laparoscopy Cause cell death by radiofrequency/ heat, ice or chemicals
34
List 6 types of percutaneous ablation of cancers
Heat: - Radiofrequency ablation - Microwave ablation/ coagulation - High intensity focused ultrasound Ice: - Cryoablation Electric: - Irreversible electroporation (IRE) Chemical: - Percutaneous ethanol injection
35
Radiofrequency ablation vs Microwave ablation of cancer cells. Which is better?
``` Radiofrequency: + Faster heat production and dissipation + Easy to use, low cost _ - charcoal accumulates at tips over time ```
36
Indication for percutaneous ablation of cancers?
Curative for small tumours Oligometastasis > limited metastatic sites Palliative symptomatic relief (e.g. decompression from mass on nerves)
37
Indications for image-guided central venous access Advantage over peripheral lines?
Drug infusion: - Antibiotics, Chemo Dialysis Resuscitation and monitoring Recurrent blood taking For prolong treatment, inject into SVC, lower risk of phlebitis and thrombosis from using limb veins
38
2 techniques to manage blocked central venous access lines
- Line stripping (e.g. fibrin deposit in catheter line during dialysis > narrow tube) - Fistuloplasty (put catheter to site of narrowing in fistula > keep using line)
39
Image-guided trans-arterial treatment for liver cancer? Indications? Mechanism?
Trans-arterial chemo-embolization (TACE) Intermediate stage HCC (supplied by hepatic arteries) Inject agents to block supplying arteries and cause tumor cell death
40
4 types of trans-arterial embolization
TAE - PVA particles for embolization TACE: cisplatin + Lipiodol TARE: Y-90 microspheres, Glass, resin DEB-TACE: Doxorubicin
41
Contraindications to TACE
Main portal vein tumour thrombosis Extrahepatic metastases Poor liver function
42
Complications of TACE
Post-embolization syndrome (massive tumour cell death release toxins): nausea, vomiting, pain, fever Cholecystitis, gastric/ duodenal necrosis, pancreatitis., liver abscess
43
Function of DEB-TACE? Advantage over normal IV chemo? Advantage over convention TACE with lipiodol?
- Soft deformable microsphere loaded with doxorubicin - Slow release of doxorubicin enhances local anti-tumor effect & decreases systemic exposure - Much easier to enhance residual active disease via CT without lipidiol
44
3 types of TARE? (radio-embolization)
Yttrium-90 (Beta-radiation) Therasphere (glass microsphere) SIR-sphere (resin)
45
Compare TACE and TARE - Occlusion of hepatic artery - Degree of embolization - Portal vein thrombosis - Bio-distribution
- Occlusion of hepatic artery TACE: occlusive TARE: not occlusive - Degree of embolization TACE: Macro-embolization TARE: Microembolization - Portal vein thrombosis Treat with TARE, not TACE - Bio-distribution TACE: drug concentrated to tumor TARE: biodistribution inconsistent
46
Which type of trans-arterial embolization is indicated before liver transplant?
TARE: Causes hypertrophy of spared/ normal parts of liver to take up functional capacity of disease lobes
47
HIFU. - Mechanism - Image guidance modality
Mechanism: - Thermal coagulative necrosis - Acoustic cavitation - Damage tumor vasculature US or MRI guidance
48
HIFU - Advantage - Disadvantage
Adv: - Avoid risk and complication of needle or electrode placement - Ability to treat large tumor >5cm Disadv: - Long treatment time - Need general anesthesia - Less precise localization