diagnostic drugs Flashcards

1
Q

What is mydriatics?

A

used to dilate the pupil ( open up)

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2
Q

what is the importance of mydriatic drugs?

A

expansion of co management schemes ( primary open angle glaucoma
-increase in professional negligence cases

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3
Q

what conditions do you dialate?

A
Diabetes 
uveitis 
pigmented fundus lesion
hypertension 
suspected glaucoma 
FH of retinal detachment 
peripheral retinal degeneration 
cataract 
AMD
history of metastic cancer
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4
Q

which symptoms do you dilate?

A
  • -Flashes or floates
  • –new distortion
  • -unexplained vision loss
    • recent blunt force trauma
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5
Q

which px do you dilate?

A
nystagmus 
squint 
stereoscopic view of retina 
systemic mediactions with potential side effects 
get good fundus photograph
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6
Q

what are the benefits for dilation?

A

ability of ophthalmoscopy to grade correctly diabetic retinopathy more 50% through dilated pupil than through undilated pupil

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7
Q

What Myrdiatics are use?

A

Tropicamide 0.5%
Tropicamide 0.1%
Phenlepharine

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8
Q

when using drugs what do you have to remember under collage of optometrist guidelines?

A

batch number
dosage
date of expiry

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9
Q

what precautions do you take with mydriasis ?

A
prev experience of mydriatic and allergy
medical history 
current medication 
iop measurment 
assessment of risk of angle closure glaucoma
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10
Q

what is most risk of px getting with mydriatics?

A

acute attack of ACG

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11
Q

what do you need to tell patient?

A
what mydriatics are for 
duration 
stings 
risks
glare problems
temp vision reduced
drivingh difficulties
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12
Q

what is the risk of provoking acute ACG?

A

more risk with phenlyepharine

no risk with tropicamide

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13
Q

what other points do you need to note for acute ACG?

A

if someone has very narrow angle should refer anyway as at high risk of attack of ACG at any time.

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14
Q

if px has suspect of retinal detachment wet AMD etc what do you do?

A

if px has retinal detachment and wet AMD you cannot obtain sufficient view must either dilate or refer on worst case scenario

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15
Q

how do you assess angle closure?

A
Van herick 
or hospital - gonioscopy 
flashlight test 
smith's slit- lenth method
methods using pachmymeters]
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16
Q

During dilation what is the most common problem?

A

glare

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17
Q

what do drivers need to be told when dilated?

A

it is recommended that driving should be avoided whilst your vision is affected

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18
Q

what is tropicamide?

A

tropicamide is an anti muscarinic drug which causes mydriasis by relaxing the sphincter muscle of the iris and cycloplegia by relaxing the ciliary muscle

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19
Q

what is the onset of action of tropicamide?

A

10-30 mins

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20
Q

what is the max effect of tropicamide?

A

20-40 mins

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21
Q

what is recovery to normal of tropicamide?

A

4-9 hours

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22
Q

how do drugs duration in patient vary?

A

individual responses to drugs are very variable

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23
Q

what are risk associated with tropicamide?

A
  • few allergic reaction
  • CNS affected can occur with cyclopentalate
  • risk of ACG in predisposed eye
  • be careful with possible interaction with other anti mscarinic drugs
24
Q

What is Phenylepharine?

A

A sympathomimetic drug which causes mydriasis by stimulating the dilator muscle of the iris

25
what is not complete with phenylepharine
mydriasis not complete | light not abolished
26
what do you use if patients are difficult to dilate?
tropicamide+ phenylepharine
27
what is the onset action of phenylepharine?
10-30 mins
28
what is the max affect of phenylepharine?
30-90 mins
29
what is the recovery to normal for phenylepharine?
5-12 hours
30
when should u not use phenylepharine ?
px with vascular hypertension & long standing insulin dependent diabetes ( type 1) long standing bronchial asthma cerebral arteriosclerosis
31
what does cycloplegic drugs do?
drug is used to produce cycloplegia | partially paralyse the ciliary muscle so that accommodation is disabled
32
when do you use cycloplegic drugs?
indication of fluctuating or excessive accommodation
33
cycloplegic drug is mainly used in?
Children | young latent hypermetropes
34
which drug is more effective if disabling accommodation in young
tropicamide and cyclopentolate are both cycloplegic agents but cyclopentolate is more effective at disabling accommodation in young people
35
what is cycloplentolate?
and anti muscarinic drug which causes mydriasis by relaxing the spincter muscle and cycloplegia by relaxing the ciliary muscle
36
what is cycloplentolate used for?
mostly used for cycloplegia not mydriasis
37
what is onset action for cycloplentolate ?
10-30 mins
38
what is max affect for cycloplentolate?
20-60 mins
39
what is the recovery to normal for cycloplentolate?
within 24 hours
40
what dosage if cycloplentolate available in?
cycloplentolate 1% cycloplentolate 5%
41
what cycloplentolate is used on which px?
cycloplentolate 1% under 12 years age | cycloplentolate 5% over 12 years age
42
which drug effect the CNS more?
cycloplentolate
43
how does colour iris effect mydriasis?
drugs bind with the melanin on the iris and is slowly released.
44
how does the action of mydriatics work on dark irides?
dark irides - -slower onset of action - longer duration of action
45
how does the action of mydriatics work on light coloured irides?
light irides - - quicker onset of action - slower duration of action
46
what are local anaesthetics used for?
used to anaesthetise the cornea and conjunctiva
47
what type anaesthetics are there?
ester type | amide type
48
what are the ester type anaesthetics and the dosage?
``` tetracaine hydrochloride (amethocaine) 0.5% oxybuprocaine hydrochloride ( benoxinate) 0.4% proxymetacaine hydrochloride 0.5% 1% ```
49
what is the amide type of anaesthetics?
lidocaine 4%
50
when do you use amide type anaesthetics?
used in previous toxic reaction to easter anaesthetics
51
what should you do before giving any drugs?
VA Vision Slit lamp IOP
52
what should you tell px when putting ocular local anaesthetics?
- complete anaesthesia within 1 min - sting on instillation - time to recovery varies usually 25 mins + - do not rub eyes - may cause toxic reaction check for staing before px leaves
53
which drug is most uncomfortable and stings?
tetracaine hydrochloride (amethocaine) 0.5% oxybuprocaine hydrochloride ( benoxinate) 0.4%
54
what are the effects of prior instillation of local anaesthetics?
corneal penetration increased by adding local aneasthetic before tropicamide or phenylepharine to give quicker response and can lead to bigger pupils
55
what is fluorescien used ?
contact applanation tonometry - goldmann contact lens fitting assessing corneal damage
56
how did fluorescien come packed in?
fluorets ( in march 2013 by bausch and lomb)
57
what is fluorescien now available in?
paper strip as a medical device