Diabetes - Part 2 Flashcards
Blood pressure in all your vasculature should be the _____.
Describe the expected values, abnormal and critical values of the ABPI/ABI.
same
1 = normal
above 1 is abnormal - e.g. calcification of arterioles in the leg
below 1 = critical - on their way to amputation
Where do we commonly find diabetic foot ulcers?
On top of the soles of the feet (footwear and metatarsals)
Describe Charcot’s foot.
Due to sensory changes, get pressure on areas not designed to handle pressure –> can lose the arch of the foot = Charcot’s foot
For the following, name what Wagner classification matches the description.
A - Superficial ulcer without SQ tissue involvement
B - Osteitis, abscess or osteomyelitis
C - Gangrene of the foot requiring amputation
D - Gangrene of the digits, or part of the foot
E - Preulcerative lesions, healed ulcers, bone deformity
F - Penetration through the subcutaneous tissue
A - 1 B - 3 C - 5 D - 4 E - 0 F - 2
What is the unique diabetic foot ulcer staging classification called?
Wagner classification
What is the colour of venous staining?
Brown-reddish colouring
Instead of going to a manicurist, where should diabetics go to get their nails cut?
Where should diabetics not moisturize?
Chiropodist/physician
Do not moisturize between toes
What was the only don’t of diabetic foot care that she pointed out?
Do not go barefoot, even in your own home
What are the treatment goals for diabetes?
1 - Maintain blood glucose consistently below 10 2 - Prevent the ABCDES of diabetes - A - AIC below 7% (6.5%) - B - control BP <130/80 C - control cholesterol <200mg/dL D - drugs (ASA to protect heart - 81mg) E - Exercise and other lifestyle measures S - stop smoking
What is the target BP for diabetics?
Less than 130/80
stimulate pancreatic insulin secretion, which in turn reduces hepatic glucose output and increases peripheral glucose disposal.
What is an example drug of this class?
Sulfonylureas
Glyburide
suppress excessive hepatic glucose production. Increasing glucose utilization in peripheral tissues
What is an example drug of this class?
Biguanides
Metformin
What is the reasoning behind biguanides being called anti-hyperglycemic agents rather than hypoglycemic agents?
Do not stimulate endogenous insulin secretion and thus cannot cause hypoglycemia (when used alone)
When are biguanides and sulfonylureas usually taken?
3x a day, before meals
What are the major insulin types?
Fast acting, intermediate acting, long acting