Diabetes Insipidus Flashcards by Victoria Osborn | Brainscape

Q

What is DI?

A

Reduced ADH causes excessive water loss

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Q

What is nephrogenic DI?

A

Poor kidney response to VP

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Q

What is neurogenic DI?

A

Hypothalamus or pituitary injury

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Q

What are symptoms of DI?

A

Polyuria, polydipsia, dehydration

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Q

What are signs of DI?

A

Dry mucosa, sunken eyes, changes to skin turgidity

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Q

How do you distinguish between nephrogenic and neurogenic?

A

Water deprivation test

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Q

What does a ADH suppression test show?

A

Neurogenic DI

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Q

What other investigations would you do?

A

Urine dipstick, glucose, U&E, fluid status

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Q

How do you manage cranial DI?

A

Rehydration, desmopressin, head MRI

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Q

What are complications of DI?

A

Dehydration, electrolyte imbalance

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Q

How much urine is passed in DI?

A

> 3L a day

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Q

What can cause cranial DI?

A

Idiopathic, congenital disorders, tumours, trauma

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Q

What can cause nephrogenic DI?

A

Inherited, low potassium, high calcium, lithium

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Q

How do you manage nephrogenic DI?

A

Rehydration, treat the cause, thiazide diuretic

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