Diabetes Insipidus Flashcards
What is an antidiuretic hormone (ADH)
controls BP and blood volume by regulating reabsorption/excretion of water in the kidneys
What do high levels of ADH cause
reabsorption of water
What do low levels of ADH cause
excretion of water
Where is ADH secreted from?
Posterior pituitary gland
When is ADH secreted?
when body senses low blood volume, low BP, and hypernatremia
What is Diabetes Insipidus?
Insufficient ADH released, resulting in kidneys being unable to concentrate urine
Neurogenic pathophysiology of Diabetes Insipidus
pituitary tumor or injury causes insufficient ADH hormone to be released
Nephrogenic pathophysiology of Diabetes Insipidus
Inadequate kidney response to ADH r/t kidney infection
Most common sign of Diabetes Insipidus
large amounts of dilute urine
What will a patients appetite look like with Diabetes Insipidus
-anorexia
What will the blood pressure of a Diabetes Insipidus patient have
hypotension
What will be the hydration status of a Diabetes Insipidus patient
- dehydration
- polydipsia (excessive thirst)
Urine lab values indicating Diabetes Insipidus
Decreased urine specific gravity (<1.005)
Decreased osmolality (<200)
Decreased sodium
Blood lab values indicating Diabetes Insipidus
- Increased osmolality >300)
- Increased sodium
What medication will be given for a patient with Diabetes Insipidus
- Vasopressin (hormone)
- Desmopressin (ADH)