diabetes Flashcards
1
Q
glipizide MOA
A
SULFONYLUREA
block K channels in the beta cells which makes the cell remain depolarized, increasing the time the cell spends in the calcium release stage, which results in signaling leading to calcium influx. The increase in calcium will initiate more insulin release from each beta cell.
2
Q
SIDE effects of glipizide
A
hypoglycemia, weight gain, hypersensitivity reactions
3
Q
metformin side effect
who should metformin not be used in
A
lactic acidosis
should not be used in people with renal disease/failure
