asthma meds

Question 1

albuterol

Answer 1

short acting b2 agonist for smooth muscle relaxation

Question 2

salmeterol

Answer 2

long acting b2 agonist for smooth muscle relaxation

Question 3

inhaled corticosteroids

Answer 3

for long term control of asthma

Question 4

beclomthasone, prednisone (oral) MOA

Answer 4

inhibit the synthesis of virtually all cytokines

Question 5

ipatropium MOA

Answer 5

muscarinic antagonist. competitively blocks muscarinic receptors preventing broncho constriction

Question 6

methylxanthine

theophylline - MOA

Answer 6

likely causes bronchodilation by inhibiting phosphodiesterase –> increasing cAMP levels

Question 7

cromolyn

Answer 7

prevents the release of vasoactive mediators from mast cells

Question 8

leukotriene antagonist

1. zileuton MOA:
2. montelukast, zafirlukast MOA:

Answer 8

1. 5-lipoxygenase pathway inhibitor. blocks conversion of arachodonic acid to leukotrienes
2. blocks leukotriene receptors

Question 9

Ketotifen

Answer 9

Use for allergic conjunctivitis where a patient has more than 2 episodes per month. Mast cell stabilizer and h1 receptor antagonist and eosinophil inh.

Question 10

Medication to be usedin a child with mild persistent asthma

Answer 10

Cromolyn.

Steroids are to be avoided if possibe in kids.