cancer drugs

Question 1

Flutamide

Answer 1

antiandrogen drug primarily used to treat prostate cancer. It acts as a silent antagonist of the androgen receptor competing with testosterone and its powerful metabolite, dihydrotestosterone (DHT) for binding to ARs in the prostate gland. By doing so, it prevents them from stimulating the prostate cancer cells to grow.

Question 2

Lupron

Answer 2

GnRH analog. Works on pituitary to interrupt the pulsatile secretion of hormone (LH and FSH), which cuts of hormone secretion.

prostate cancer, endometriosis,

Question 3

5 fu

Answer 3

Thymidylate synthase inhibitor. Used in colon ca

Question 4

Leucovorin aka folinic acid

Moa

Answer 4

Bone marrow rescue.

Good to use with methotrexate overdose. And 5fu.

This is synthetic dihydrofolate. Useful because not affected by methotrexate.

Question 5

Etopiside

Answer 5

Dna strand breakage.

Prevent strands from reassembly.

Question 6

Tamoxifen

Answer 6

Estrogen receptor antagonist. Use in hormone receptor positive breast cancer. Useful in premenopausal women.

Question 7

Bevacimab

Answer 7

Monoclonal antibody. Angiogenesis inhibitor. Vegf inhibitor.