Diabetes 2 Flashcards
Diabetes Mellitus
Metabolic disorder characterized by high blood glucose levels and altered metabolism of proteins and fats; associated with thickening of the basement membrane
Glyocgen
Storage form of glucose
Glycosuria
Presence of glucose in the urine
Hyperglycemia
> 106 mg/dL
Hypoglycemia
<40 mg/dL
Incretins
Peptides in the GI that help modulate insulin and glucagon
Insulin
Hormone produced by beta cells in the pancreas; stimulates insulin receptor sites to move glucose into the cells; promotes storage of fats and glucose
Ketosis
Breakdown of fats for energy, resulting in an increase in ketones to be excreted from the body
Polydipsia
Increased thrist; seen in diabetics when loss of fluid and increased tonicity of the blood lead to hypothalamic thirst center to make the patient feel thirsty
Nervous System Glucose
Must receive glucose by diffusion, no receptors.
Too Much Glucose in Nerves
Draws in water, edema.
Too Little Glucose in Nerves
Decrease function
Basement Membrane
Thin layer of collagen filament that lies just below the endothelial lining of blood vessels
Basement Membane Damage Increases Diseases: 4
Artherosclorosis
Retinopathy
Neuropathies
Nephropathy
HB1AC
Glycosylated Hg Levels - 3 month average