Coagulation 2

Question 1

Disseminated Intravascular Coagulation

Answer 1

Small blood clots blocking microvasculature

Numerous clots depletes platelets, leading to increased bleeding

Question 2

Fibrinogen

Answer 2

Converted to Fibrin by thrombin, forms clots

Question 3

Plasminogen

Answer 3

Converted to Plasmin, breaks down fibrin, dissolves clots

Question 4

Hemophilia

Answer 4

Genetic lack of clotting factors, uncontrolled bleeding

Question 5

Liver Disease

Answer 5

Decreased production of clotting factors and proteins

Question 6

Bone Marrow Disorders

Answer 6

Platelets are not formed in sufficient quantity

Question 7

Which pathway does Heparin work in?

Answer 7

Intrinsic

Question 8

Does Heparin lyse current clots?

Answer 8

No

Question 9

What does Heparin prevent?

Answer 9

Formation of blood clots

Question 10

What is Heparin drip protocol based on?

Answer 10

aPTT

Question 11

Can you give IM heparin?

Answer 11

No, potential for hematoma

Question 12

Side effect of long term Heparin use?

Answer 12

Osteoporosis, hair loss, rash