Diabetes Flashcards
Diabetes Mellitus
secreted by:
of the :
INSULIN- from pancreas a hormone secreted by the BETA CELLS of the ISLETS OF LANGERHANS in the PANCREAS in response to an INCREASE
How much units
40-60 units secreted by pancreas
Normal blood glucose range
74-106 mg/dl
Insulin
AIDS in transport and metabolism glucose for energy
Glucagon
Glucose in liver storage
Insulin role (5)
Stimulates storage of glucose in the liver as glycogen
*Signals the liver to stop the release of glucose
*Enhances the storage of dietary fat in adipose tissue
*Accelerates protein synthesis into cells of the muscles
*Facilitates the release of stored glucose, protein from muscle and fat from adipose tissue
Polyphagia
Increase hunger
Polydypsia
Increased thirst
Glycouria
Sugar in urine
3 p’s in db type 1
s/s (4)
Polyuria, Polydipsia, Polyphagia
quick onset/ less than 30/ normal or under BMI/ ketones
type 1 vs type 2
type 1: insulin deficiency. autoimmune. Requires insulin therapy.
type 2: (lifestyle) insulin resistant. receptor cells are resistant to insulin. Can be genetic.
type 2 s/s (6)
Chronic
Frequent infections (yeast infections)
-prolonged wound healing
Numbness+ tingling in hands and feet
Fatigue (harder to diagnosis)
Blurred vision
risk for type 2:
waist
triglycerides
HDL
BP
Fasting Glucose ( state normal)
waist: men greater than 37 inches
women greater than 33
triglycerides greater than 150
men less than 40
women less than 50
greater than 130/85
greater than 106 (Normal is
74-106mg/dl)
RISK FACTORS FOR TYPE II
DM (9)
- Obesity- 25 lbs. above ideal weight (abdominal
fat) - Hereditary
- Age >45 years
- Stress
- Race: African American, Native American, Hispanic,
Asian American and Pacific Islanders - Sedentary lifestyle
- Dx of Prediabetes or gestational DM
- Hypertension
- High Cholesterol
GESTATIONAL DIABETES (4)
whenare moms screened/risk factors 3
Occurs in 2 -10%
pregnancies in US
Increases the risk of C-
section delivery,
Preeclampsia and fetal
macrosomia
Risk factors include obesity,
advanced maternal age,
family hx of DM
Moms screened at 24-28
wks with OGTT (oral glucose
tolerance test)
SECONDARY DIABETES ( 3)
Associated with pancreatic & endocrine
disorders such as Cushings syndrome,
acromegaly
Use of certain medications such as
corticosteroids (prednisone), estrogen,
thiazides
Contribute to diabetes d/t damages to the B-
cell functioning in the pancreas
PREDIABETES
(define/ IFG/ IGT/interventions *2)
Blood sugar levels elevated but not high enough to be classified as diabetic- most
likely will progress to type 2
- IFG: Fasting blood glucose levels 106-
125mg/dl - IGT: Glucose tolerance test 140-199mg/dl
Interventions :
a. Losing weight and increase activity may prevent or delay DM
b. Monitor blood glucose levels, HgA1C levels,
assess for s/s DM
**DIAGNOSIS OF DM **
Fasting Plasma Glucose=
Confirmed by:
A1C= * remember what professor d said*
Fasting=
2hr =
Glucose Tolerance =
- Fasting plasma glucose > 126
- Confirmed by repeat test on another day:
preferred - A1C lab result 6.5% or higher !
- 2 hr Oral glucose tolerance test (OGTT)
- Fasting at least 8hr, drink glucose liquid (75gm),
blood drawn before liquid and again at 60 mins
after and 120 mins after consumption. - 140-199 Prediabetes
urine = negative
- Glucose tolerance >200 confirms DM