DFI Flashcards
Risk Factors
- ___
- angiopathy/ischemia
- immunologic defects
- poor wound healing
- neuropathy
Diagnosis
Patient Presentation
- typical ___ signs of infection, +/- ___ secretions
- more specific to DFI: discolored tissue, foul odor
Cultures
- Wound cultures: NOT recommended for ___ infection
- Bone cultures: typically obtained following incision and drainage
- Blood cultures: may be considered
- local, purulent
- mild
Causative Pathogens - DFI
Infected Ulcers (2)
- S. aureus
- Streptococci spp.
Causative Pathogens - DFI
Chronic Infected Ulcers (4)
- S. aureus
- Streptococci spp.
- Enterobacteriaceae spp.
- Anaerobes
Causative Pathogens - DFI
Macerated Ulcer due to Soaking
- S. aureus
- Streptococci spp.
- P. aerogenes
Causative Pathogens - DFI
Chronic Non-Healing Ulcers (5)
- S. aureus
- Streptococci spp.
- Enterococcus spp.
- P. aerogenes
- Anaerobes
MRSA Risk Factors
- previous MRSA infection within past ___
- local MRSA prevalence > __ - __ %
- recent ___
- failed non-MRSA antibiotics
- year
- 30-50%
- hospitalization
Pseudomonas Risk Factors
- Hx of pseudomonas infection
- ___ feet in water
- ___ climate
- ___ infection
- failed non-pseudomonal Abx
- Soaking
- warm
- severe
Overall Management
- ___ intervention
- ___ control
- Abx
- surgical
- glycemic
Managemnt: Mild
Need to cover: ___ and ___ spp.
First Line:
- ___
- ___
- ___
Duration: __ - __ weeks
Recent Abx? Switch to:
- ___ / ___
- ___ or ___
MRSA Risk Factors? Switch to:
- ___ / ___
- ___
- MSSA, Streptococci
- dicloxacillin, cephalexin, clindamycin
- 1-2
- amoxicillin/clavulanate
- levofloxacin, moxifloxacin
- SMZ/TMP, doxycycline
Management: Moderate
Need to cover: MSSA, Streptococci spp., ___ , and ___
First Line
- ___
- ___ / ___
- ___ or ___ + ___ or ___
Duration: __ - __ weeks
Pseudomonal Risk Factors? Switch to:
- ___ or ___ + ___ or ___
MRSA Risk Factors? ADD
- ___
- ___
- ___
- ___ / ___
- Enterobacteriaceae, anaerobes
First Line
- moxifloxacin
- Amoxicillin/clavulanate
- ciprofloxacin or levofloxacin + clindamycin or metronidazole
2-3
Pseudomonal Risk Factors
- ciprofloxacin or levofloxacin + clindamycin or metronidazole
MRSA
- doxycycline
- linezolid
- vancomycin
- sulfamethoxazole/trimethoprim
Management: Severe
Need to cover: MSSA, Streptococci spp., Enterobacteriaceae, Anaerobes, ___
First Line:
- __ / ___
- ___
- ___ + ___ or ___
Duration: __ - __ weeks
MRSA Risk Factors? ADD
- ___
- ___
- ___
Pseudomonas
First Line:
- pipericillin/tazobactam
- carbapenem
- cefepime + clindamycin or metronidazole
2-3
MRSA
- vancomycin
- linezolid
- daptomycin
