developmental processes, clinical science & genetics Flashcards

1
Q

increased risk for sporadic schizophrenia

A

advanced paternal age

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2
Q

conservation of liquid

A

concrete operational stage

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3
Q

Margaret Mahler’s sequence of infant developement

A

autistic phase, symbiotic phase, separation-individuation

autistic- first weeks of life, total detachment and self absorption, most time sleeping

symbiotic phase- until about 5 mo old, infant recognizes mother but lacks sense of individuality

separation individuation has 3 phases:

  1. hatching- infant shows increased interest in outside world.
  2. practicing (9-16 mo)- infant develops physical ability to separate from mother
  3. rapprochment (15-24 mo), infant explores outside world but requires mother to be present and to be able to support child in task emotionally
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4
Q

klinefelter syndrome

A

meiotic nondysjunction
males have extra X chrom
47 XXY

tall, long extremities, testicular atrophy, gynecomastia, developmental delay
higher mortality from breast cancer

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5
Q

ages of different plays

A

2- parallel play
3- associative
4- cooperative

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6
Q

genes in human genome

A

25k

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7
Q

extinction

A

loss of previously learned operant response after no longer reinforced by a stimulus

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8
Q

Erick Erikson 8 stages of development

A
  1. trust v mistrust (birth to 18m): basic trust

2, autonomy v shame (18 mo-3y)- toddlers need to do things themselves; control and dependence

  1. initiative v guilt (3-6yo)- early childhood: kids learn how to exert themselves, guilt if not supported, finding purpose, taking control of environment
  2. industry v inferiority: (6-up to age 12)- self confidence and self interests and abilities. competence, social skills (going to school)
  3. Identity v role confusion: (ages 12-19); develop self identity and determine how they will fit into society in adulthood. identity and commitment
  4. intimacy v isolation (18y-35)- ability to form close attachments with others, including romantic, commitment
  5. generativity vs stagnation (35-65)- middle adulthood, where an individual faces question of how to contribute to society
  6. ego integrity v despair (65 to death): late adulthood, looking back over accomplishments and determining if they are fulfilled or dissatified.
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9
Q

concrete operational stage

A

piaget

learn rules around ags 7-11 such as conservation,
decentering (multiple aspects of a problem to solve it), reversibility (understanding numbers can be changed and return to original state), transivity (ability to sort objects mentally and recognize relationships among things in a series).

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10
Q

oedipal complex

A

Freud’s theory
phallic phase
a boys unconsious desire to possess his mother sexually and kill his father
castration anxiety are boys who have guilt from oedipal complex
starts during PHALLIC phase

phallus phase: girls have penis envy, age 3-5

age 12-18 genital phase

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11
Q

critical period

A

stage in lifespan of organism in which nervous susten is sensitve to environmental stiumuli
If they don’t receive appropriate stimulus during this time to learn a skill, they may not learn it.

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12
Q

heritable risk of suicidal behavior

A

relatives of suicide completers and attempters have heritable risk of SAs and completions

4x as high

twins 40-55%

adoptions studies suggest gentic component

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13
Q

small molecule transmitters

A

GABA, glutamate, glycine, ach, serotonin, dopamine, norepinephrine, histamine

stored in small sunaptic vesicles and mediate FAST synaptic tranmission

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14
Q

stored in large gnse core vesicles

A
somatostatin
hypothalamic releasing hormone
endorphins
enkephalins
opiods
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15
Q

herb shown to be effective in anxiety DOs

A

kava kava

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16
Q

SSRI for people with CAD

A

zoloft

improves endothelial function, reduce platelet activation
modify centrally mediated autonomic function
improve QOL with MDD and CAD

17
Q

when to hospitalize anoroxia

A

> 25% below expected weight or children rapidly losing weight

refeeding syndrome: prolongation of QT and hypophophatemia

olanzapine shown effective for WG in anorexia

18
Q

Refeeding sydnrome

A
hypophosphatemia 
hyopkalemia
CHF
peripheral edema
rhabdomyolysis
seizures
hemolysis
QT prolongation 
AMS
ventricular arrythmias
proximal myopathy an dileus
red cell hemolysis 
thrombocytopenia
white cell phagocytosis 

TX: oral sodium phosphate

19
Q

Winnicott

A

known for transitional object, representing mother’s presence

20
Q

Piaget known for

A

cognitive development. Assimilation and acoomodation to describe how individuals adapt to new info.

assimilation: take in new information and incorporate into existing ideas
accommodation: revising existing cognitive schemas, perceptins, understandng

21
Q

anna freud

A

“developmental lines”
decribes continuous and cumuative process of character develpment

father freud emphasized interactions and interdependencies in stepwise process

22
Q

Maline Klein

A

extended and developed freud’s concept of unconscious mind

inner life of infant is rich with aggressive sexual fantasies.
reparation is concept used to make mental repairs to damaged inner world and is key to move from paranoid-schizoid position into depressive

23
Q

chess and thomoas

A

defined temperment

24
Q

john bowldy

A

developed attachment theory. innate need to attach to one person for survival.

25
Q

hippocampus forms memory by

A

long term potentiation of synaptic connections.

short term memory involves modification of existing proteins in response to stimuli.

26
Q

forebrain

A

telencephalon: cerebral hemispheres, lateral ventricles
diencephalon: thalamus, hypothalamus, epithalams, retina, pineal gland , third ventricle

27
Q

midbrain

A

mesencephalon:

midbrain, cerebral aquaduct

28
Q

Hindbrain

A

metencephalon: pons, cerebellum, upper part of 4th ventricle
myelencephalon: medulla, lower part of 4th ventricle.

29
Q

Jean Piagets stages of cognitive development

A

sensorimotor: 0-2y
preoperational: 2-7yo

concrete operations: 7-12y

formal operations: 11 to adulthood

30
Q

freud’s psychosexual stages

A

oral: 0-18m
anal: 18m-3y
phallic: 3-5y
latency: 5-12 y
genital: 12-15y

31
Q

androgen insensitivity syndrome

A
genetically male (46 xy)
but body can't respond to androgens so they have  female external sex characteristics
32
Q

mullerain agenesis

A

secondary sex characteristic female, short vagina, no uterus

XX

33
Q

5 alpha reductase def

A

genetic males 46 XY unable to convert testosteroe to DHT

ambuguous genitalia until puberty when testosterone promotes masculization

34
Q

aromatase deficiency

A

cant convert estrogens FROM androgens , causing masculization of females

46 XX

infants have ambiguous genitalia

35
Q

karen horney

A

real self vs idealized self

social and cultural influnces on psychosexual development

“holistic psychology” a personal strives to be seen as a unitary whole

therapy is allowing person to strive for self realization by understanding distortions that prevent personality from growing.

36
Q

DiGeorge syndrome

A

22q11 deletion, autosomal dominant

CATCH-22

Cardiac abnormality, tetrology of fallot

Abnormal Facies

Thymic Aplasia

Cleft palate

Hypocalcemia/Hypoparathyroidism
_

Development delay, speech delay
comorbid psych disorders, psychosis in 30%,