Developmental Anomalies Flashcards
Cleft lip is the result of
Lack of fusion between the medial nasal process with lateral portions of the maxillary process
When does cleft lip happens in intrauterine life
6th and 7th week
Cleft palate is characterized by
Fissure in the midline of the palate due to failure of fusion if palatal shelves of the max process
Most common form of craniofacial malformation of the head and neck
Cleft lip
Cleft palate
Dental problems in cleft lip and palate patients
Malocclusion
Crown defects
Missing teeth -lateral incisors
Supernumerary teeth
Paramedian lip pits
Congenital invaginations of the lower lip
Bilateral symmetric
Vander woude syndrome
Autosomal dominant
Presence of lower lip pit
Cleft lip/and palate
Inherited disease characterized by aplasia or hypoplasia of ectodermal structures
Ectodermal dysplasia
Most common type of ectodermal dysplasia
Hypohidrotic form
X linked recessive inheriitence
Females are carriers
Males are affected
Clinical findings of ectodermal dysplasia
Smooth dry skin
Hypotrichosis - blonde hair eyebrows
Anhidrosis - no sweat glands, heat intolerance
Midface hypoplasia
Dystrophic and brittle nails
Xerostomia
Depressed bridge of the nose
Dental findings in ectodermal dysplasia
Anodontia
Oligodontia
Conjcal crowns tapered and pointed
Autosomal dominant disorder affects face skull and clavicles
Cleidocranial dysplasia - dystotosis
Mutation in which gene results in cleidocranial dysplasia
RUNX2
Hypoplasia or aplasia of clavicles
Hyper mobility of shoulders
Defective ossification of skull
Large prominent frontal eminence
Ocular hypertelorism
Broad base nose shortened skull
Cleidocranial dysplasia
Oral findings in cleidocranial dysplasia
Over retention of deciduous teeth
Failure of eruption of permanent teeth
Numerous supernumerary teeth
Dentigerous cysts
Most common syndrome to have supernumerary teeth
Cleidocranial dysplasia
Inherited developmental disorder in neonates characterized by cleft palate
Micrognathia
Hypoplasia and retognathia of mandible
Glossoptosis
Pierre robin syndrome
Autosomal dominant condition characterized by malformations of the skull- craniosystosis(premature fusion of sutures) acrobrachycephaly (tower skull), mid third retrusion and hypoplasia, mandible prognathism
Apert syndrome
Acrocephalosundactyly
Intraoral findings of apert sydrome
Bifid uvula
Class 3 malocclusion
Crowding
Cleft palate
Ant open bite
Ant and post crossbite
Shovel shaped incisors
Delayed eruption and missing teeth
Autosomal dominant craniofacial disorder characterized by craniosynostosis, orbital cavity deformities, bracycephaly (short head) , shallow orbits, ocular proptosis, hypertelorism and increased intracranial pressure
Crouzon syndrome
Intraoral manifestations of crouzon syndrome
Midface hypoplasia
Mand prognathism
Crowding in max
Bilateral post crossbites
Beaten metal app on skull xray due to increased intracranial pressure is seen in
Crouzon syndrome
Calcified stylohyoid ligament is seen in
Eagle syndrome
Rare genetic disorder characterized by absent or hypodontia of teeth
Mild craniofacial abnormalities, glaucoma, flattened face, hypolastic maxilla, protruding lower lip
Riegers syndrome
Dental findings in riegers syndrome
Hypoplastic maxilla
Protruding lower lip
Microdontia
Hypodontia
Conical crowns
Enamel hypoplasia
Teeth malposition
Autosomal dominant disorder characterized by developmental anomalies derived 1st and 2nd branchial arches
Treacher Collin syndrome
Mandibulofacial dysostosis
Features of treacher collin syndrome
Hypoplastic zygoma - narrow face
Hypertelorism
Depressed cheeks
Downward slanting eyes
Ear defects
Hypolastic nasopharyx and oropharyx
Oral findings treacher collin syndrome
Mandibular hypoplasia retruded chin
Cleft palate
Severe mid face deficiency
Malocclusion
Flatted or aplastic condyle and coronoid process
Patient is short stocky build broad and flat face mid skeletal def ocular HYPOTELORISM upward slanting eyes flattened nose
Down syndrome
Oral manifestations of down sydrome
Macroglossia with fissures
Mouth breathing
Open bite
Perio disease
Delayed eruption
Hypondontia
Microdontia
Post crossbite
Malocclusion
High arch palate
Ankhloglossia
Limitations of tongue movement due to short thick lingual frenum
Speech problems
Localised gingival recession of lower incisors
Fissured tongue is associated with
Down syndrome
Geographic tongue
Melkersson rosenthal syndrome
If condylar hyperplasia is on right side
Jaw will deviate towards?
Unaffected side
If the condyle is hypoplastic
Jaw will shift to
Affected side due to weakness
Hemihyperplasia is associated with
Neurofibramatosis
McCune albright syndrome
Intraoral manifestations of hemihyperplasia include
Unilateral macroglossia
Malocclusion
Crown and roots - large or prematurely developed
Eruption problems
Oral manifestation of cerebral palsy
Enamel hypoplasia
Delayed eruption
Class 2 malocclusion
Open bite
Mouth breathing
Gingival hyperplasia
