Development of the Nervous System

Question 1

gray matter

Answer 1

location of cell bodies of neurons

cell bodes or unmyelinated axons

Question 2

white matter

Answer 2

location of axons

Question 3

dorsal (posterior) horn

Answer 3

sensory

Question 4

lateral horn

Answer 4

autonomics

Question 5

ventral (anterior) horn

Answer 5

motor

Question 6

dorsal (posterior) funiculus

Answer 6

sensory (ascending to the brain)

Question 7

lateral funiculus

Answer 7

sensory and motor

Question 8

anterior (ventral) funiculus

Answer 8

primary motor

Question 9

alar plate

Answer 9

sensory

Question 10

basal plate

Answer 10

motor

Question 11

sulcus limitans

Answer 11

separates alar and basal

Question 12

ventricular zone

Answer 12

stem cells, form choroid plexus cells which secrete cerebral spinal fluid

Question 13

intermediate zone (mantle layer)

Answer 13

neurons, glials, astrocytes (cell bodies) grey matter

Question 14

marginal zone

Answer 14

axons from neurons are found, myelinated by oligodendrocytes in CNS, white matter

Question 15

microglial cells come from

Answer 15

mesoderm

Question 16

high BMP activate ____ and ____ = ______ differentiation= _____ plate

Answer 16

PAX 3 and 7= sensory neuron differentiation= alar plate

Question 17

high SHH levels activate ____ and ____ = _______ formation = _____ plate

Answer 17

NKX2.2 and NKX6.1= ventral neuron formation= basal plate

Question 18

just dorsal there are slightly lower levels of ___ and higher levels of ___ which activate ____ and ____= _______ neurons

Answer 18

SHH, BMP, NKX6.1 and PAX6= ventral motor neurons

Question 19

GSE

Answer 19

motor, somatic (skeletal) muscle

Question 20

GVE

Answer 20

autonomics to smooth and cardiac muscle and glands

Question 21

SVE

Answer 21

muscles derived from pharyngeal arches (face, head and neck)

Question 22

GSA

Answer 22

sensory in the skin, joint capsule, tendon muscle

structures that either came from ectoderm or came from mesoderm that was close to ectoderm

Question 23

GVA

Answer 23

sensory of the visceral structures (lungs, GI)

structures either from endoderm or mesoderm that was close to endoderm

Question 24

SSA

Answer 24

hearing, balance, sight

Question 25

SVA

Answer 25

taste and smell, chemical senses

Question 26

Hirshprang’s disease

Answer 26

megacolon

defect in neural crest cells (post-ganglionic parasympathetics)

Question 27

_______ are the cells that myelinate in CNS

Answer 27

oligodendrocytes

6th month through puberty

Question 28

______ are the cells that myelinate in PNS

Answer 28

Shwann cells, motor roots myelinated before sensory roots

4th month en utero