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MSK > Cartilage > Flashcards

Cartilage Flashcards

1
Q

which layer of articular cartilage?

A

transitional layer

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2
Q

repair of damaged cartilage is due primarily to activity of ______

A

perichondrium

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3
Q

interstitial vs appositional growth

A

interstitial: legth
appositional: width

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4
Q

cartilage fxns

A

bear mechanical stress shock absorber frictionless joint movement bone growth fracture repair

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5
Q

outer fibrous layer

A

contains fibroblasts which produce type I collagen and elastin

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6
Q

fibrocartilage organization

A

chondrocytes in parallel rows, collagen fibers in bundles (type I and II)

ground substance has dermatan and chondroitin sulfate

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7
Q

which type of collagen predominates matrix

A

type II (type I in fibrocartilage, elastic fibers in elastic cartilage)

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8
Q

perichondrium

A

dense CT, carries blood supply, source of new cartilage cells

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9
Q

proximity of BV often stimulates _______ instead of cartilage repair

A

bone growth (osteoblasts)

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10
Q

fibrocartilage and where found

A

NO perichondrium type I C found in IV disks, articular disks of knee, mandible, sternoclavicular joints, pubic symphysis

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11
Q

label the layers

A

top to bottom: tangential layer, transitional layer, radial layer, calcified cartilage, bone

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12
Q
A

hyaline

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13
Q

chondroblasts vs chondrocytes fxns

A

blast: replicating population that SECRETE matrix cyte: MAINTAIN matrix

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14
Q

amphiarthroses joints permit _____ and are found ______

A

slight movement

intervertebral disks and bodies

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15
Q

which layer of articular cartilage

A

radial layer (the stacks of cells are oriented perpendicular to the articulating surface)

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16
Q

type A macrophage-like synovial cells

A

phagocytic

contain lysosomes to clear articular cavity of debris

17
Q

what type

A

fibrocartilage (tendon)

18
Q

which layer of articular cartilage?

A

calcified cartilage

19
Q

except for ___________, hyaline cartilage is surrounded and nourished by perichondrium

A

articular surfaces

20
Q

type B fibroblast-like synovial cells

A

produce synovial fluid

hyaluronic acid to increase viscosity

lubricin

lubricates cartilage to reduce friction

21
Q

articular cartilage

A

type of hyaline cartilage that does not have perichondrium

reduces friction between bones

no nerves or BV

22
Q
A

hyaline

23
Q

cartilage characteristics

A

composed of cells and ECM cells are chondroblasts or chondrocytes avascular no nerve supply no lymphatics

24
Q

hyaline and where found

A

has perichondrium type II C found in embryo, articular cartilage of resp tract, costal cartilage

25
Q

inner chondrogenic layer

A

gives rise to chondroblasts and osteoprogenitor cells

blasts secrete type II collagen

26
Q

elastic and where found

A

has perichondrium type II C and EF found in external ear, epiglottis, auditory tube

27
Q

synovial membrane

A

surrounds entire joint cavity except articular cartilage

regenerates if damaged

28
Q

what type/label arrows

A

hyaline

starting upper left and going clockwise: outer fibrous layer, inner chondrogenic layer, territorial matrix, interterritorial matrix, chondrocytes

29
Q

cartilage is usually replaced by______

A

dense CT or bone (if vascularized)

30
Q

territorial matrix

A

surrounds isogenous cell group, high amt of GAGs and lower amt of collagen

31
Q

chondrocytes

A

round cells with small dark nuclei

arranged in lacunae

often in groups of 2-8 cells (isogenous groups)

32
Q

what type/what is arrow pointing to?

A

hyaline, perichondrium

33
Q

diarthroses joints permit ______ and are found______

A

free movment

synovial joints

34
Q

interterritorial matrix

A

surrounds territorial matrix, more collagen II and fewer GAGs

35
Q

what type

A

elastic

36
Q

Which layer of articular cartilage?

A

tangential (chondrocytes flattened parallel to surface, cartilage parallel to surface)

37
Q

what type

A

Elastic

38
Q

synarthroses joints permit _____ and found in ______

A

little to no movement

cranial bones, ribs, sternum

39
Q

what type

A

fibrocartilage

MSK (13 decks)

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