Bone Histology

Question 2

periosteum

Answer 2

CT covering bone highly neurovascular contains osteoblasts

Question 3

Sharpey’s fibers

Answer 3

anchoring collagen fibers penetrate the outer circumferential lamellae

Question 4

endosteum

Answer 4

CT lining of the marrow cavity of the bone contains osteoblasts

Question 5

Metaphysis

Answer 5

spongy bone between end of diaphysis and epiphysis

Question 6

spongy bone (trabecular or cancellous)

Answer 6

lamellar or woven

Question 7

woven bone

Answer 7

immature/primary loose arrangement of collagen fibers lower mineral content, more cells

Question 8

lamellar

Answer 8

mature/secondary bone parallel arrangement of collagen fibers

Question 9

what type of bone

Answer 9

woven

Question 10

achondroplasia characteristics/causes/what zone?

Answer 10

long bones affected, not cranial or vertebral bones

due to FGFR3 mutation (this gene controls signal that stops chondrogenesis), so cartilage not formed, premature ossification of growth plates

zone: proliferative zone

Question 11

what type of bone

Answer 11

lamellar

Question 12

epiphyseal line

Answer 12

where epiphyseal plate fused, located in metaphysis

Question 13

intramembranous ossification

Answer 13

uses mesencymal template

bones: frontal/parietal/occipital/temporal/mandible/maxilla/clavicle

Question 14

organic components of bone

Answer 14

type I collagen fibers proteoglycans noncollagenous proteins (osteocalcin, osteopontin, osteonectin)

Question 15

what type of bone

Answer 15

lamellar

Question 16

endochondral ossification

Answer 16

uses cartilage template

bones formed: parst of basicranium, long bones, pelvic and pectoral girdles, ribs

Question 17

compact bone

Answer 17

encloses spongy bone lamellar

Question 18

diaphysis

Answer 18

shaft, compact bone surrounding marrow cavity

Question 19

epiphysis

Answer 19

ends of the bone spongy bone surrounded by thin compact bone contains growth plate (epiphyseal plate)

Question 20

osteomalacia and rickets lab values?

calcium:

phosphorus:

alkaline phosphatase:

Answer 20

calcium: decreased or normal
phosphorus: decreased or normal

alkaline phosphatase: increased

Question 21

what type of bone

Answer 21

woven

Question 22

inorganic components of bone

Answer 22

calcium hydroxyapatite, magnesium, potassium, sodium, fluoride