Development of Pharyngeal Arches Flashcards
What are the three main components of a pharyngeal arch?
- Mesenchymal core (from mesoderm and neural crest)
- Internal ectoderm pouch
- External cleft (ectoderm)
How many pharyngeal arches are there?
5
Pharyngeal arches 1, 2, 3, 4, (5 disappears) and 6
What is the stomodeum?
ending of GI gut tube
What are the two prominances of the 1st pharyngeal arch?
- upper maxillary
- lower mandibular
What are the two main sources of mesenchyme for each arch and what do they give rise to?
Each arch has a mesenchyme core from two main sources –
mesoderm and neural crest:
o Muscle (brachial muscles)
o Cartilage element
o Artery
o Cranial Nerve
What happens to paraxial mesoderm in the pharyngeal arches?
migrates into pharyngeal arches and elsewhere to form mostly muscle tissue of head (and some connective tissue/bone)
What is the contribution of the lateral plate mesoderm to the head?
Small
What is the function of the neural crest and the ectodermal placodes?
- Neural crest (ventral flow around placodes and into
pharyngeal arches – mesenchyme, ganglia, nerves)
- Ectodermal placodes (thickening of ectoderm that can
help give rise to sensory neurons
What are the muscles of the 1st pharyngeal arch?
- muscles of mastication
- anterior belly of digastric
- mylohyoid
- tensor tympani
- tensor vali palatini
What are the muscles of the 2nd pharyngeal arch?
- muscles of facial expression
- stylohyoid
- strapedius
- posterior belly of digastric
What are the muscles of the 3rd pharyngeal arch?
Stylopharyngeus
What are the muscles of the 4th pharyngeal arch?
- All muscles of the pharynx except stylopharyngeus
- All muscles of the palaye except tensor veli palatini
- Cricothyroid
What are the muscles of the 6th pharyngeal arch?
All the muscles of the larynx
What are the skeletal features of the 1st pharyngeal arch?
- Maxilla
- Zygomatic bone
- mandible
- malleus
- incus
- meckel’s cartilage
What are the skeletal features of the 2nd pharyngeal arch?
- Stapes
- styloid process
- stylohyoid ligament
- lessor horn of hyoid
- upper part body of hyoid