Development of Nervous System Flashcards

1
Q

Where does the nervous system and notochord originate form?

A

nervous system - ectoderm

notochord - mesoderm

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2
Q

What are the five vesicles?

A
Telencephalon
Diencephalon
Midbrain
Metencephalon
Myelencephalon
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3
Q

Neural Crest cells

A
PNS
cranial nerve sensory ganglion cells
dorsal root ganglion cells
postganglionic autonomic ganglion cells
chromaffin cells of the adrenal medulla
Schwann cells
melanocytes
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4
Q

3 layers of neural tube

A

Ventricular (innermost)
mantle (gray)
marginal (white)

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5
Q

midpoint of neural canal

A

Sulcus Limitans

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6
Q

Where do neurocytes migrate in the developing spinal cord

A
Dorsal = Alar plate = sensory
Ventral = Basal plate = motor
Intermediate = autonomics = lateral horn
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7
Q

Which foramen are associated with the 4th ventricle?

A

Foramen of Luschka (lateral)

Foramen of Magendie (medial)

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8
Q

Where is CSF made?

A

Choroid Plexus (thickening of pia)

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9
Q

Parts of the Pons

A

Dorsal - tegmentum

Ventral - basilar

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10
Q

What does the metencephalon form?

A

Pons & cerebellum

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11
Q

What does myelencephalon become?

A

Medulla

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12
Q

What does mesencephalon become?

A

Midbrain

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13
Q

Parts of the midbrain?

A

tementum (continuation medially)
tectal (dorsal)
peduncular (ventral) (crus cerebri)

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14
Q

What does diencephalon become?

A
thalamus (dorsal)
hypothalamus (ventral)
Pineal
Choroid plexus
optic vessicles
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15
Q

What does telencephalon become?

A

cerebral hemisphere, basal ganglia, hippocampus, amygdala

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16
Q

Spina Bifida (myeloschisis)

A

not fully closed vertebra

17
Q

Spina Bifida cystica (two types)

A

meningocele - CSF is sticking out

meningomyocele - neural tube outside of body

18
Q

Rachischisis

A

problem with neural tube formation

19
Q

Meningocele

A

CSF herniation

20
Q

Meningoencephalocele

A

brain tissue & CSF

21
Q

Meningohydroencephalocele

A

ventricles & brain tissue & CSF

22
Q

Arnold-chiari

A

caudal displacement of posterior cranial fossa structures (cerebellum) through foramen magnum

23
Q

Microcephaly

A

cranial vault smaller than normal

24
Q

Dandy-walkery syndrome

A
phenotype: dramatic or imperceptible
4th ventricle enlargement
medial and lateral apertures not found
absence of cerebellar vermis
cysts form on internal base of skull
25
Q

Hydrocephaly

A

accumulation of CSF

usually blockage of cerebral aqueduct

26
Q

Anencephaly

A

missing cranial vault

brain usually necrotized

27
Q

Craniorachischisis

A

issue with brain and spinal cord